Lung ultrasound score based on the BLUE-plus protocol is associated with the outcomes and oxygenation indices of intensive care unit patients
Lung ultrasound score based on the BLUE-plus protocol is associated with the outcomes and oxygenation indices of intensive care unit patients
复制标题
基于 BLUE-plus 方案的肺部超声评分与重症监护病房患者的结局和氧合指数相关
DOI：
10.1002/jcu.23024
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发表时间：
2021-06-11
影响因子：
0.9
通讯作者：
Zhang, Li-Na
中科院分区：
文献类型：
--
作者：
Peng, Qian-Yi;Liu, Li-Xia;Zhang, Li-Na
目的探讨肺部超声（LUS）表现与重症监护病房（ICU）患者预后的关系。次要目的是确定LUS表现在不同亚组的ICU patients.Methods前瞻性多中心队列研究的特点进行了17个ICU。共纳入2017年8月31日至2019年2月16日期间收治的1702例患者。根据床旁肺部超声急诊（BLUE）-plus方案进行LUS，并计算LUS评分。结果LUS评分明显高于非生存者，氧合指数组间差异有统计学意义，氧合指数较低组评分更高。LUS评分是28天死亡率的独立危险因素。预测28天死亡率的受试者工作特征曲线下面积为0.663，预测氧合指数为0.748
Purpose The primary objective was to demonstrate the relationship between lung ultrasound (LUS) manifestations and the outcomes of intensive care unit (ICU) patients. The secondary objective was to determine the characteristics of LUS manifestations in different subgroups of ICU patients.Methods This prospective multi-center cohort study was conducted in 17 ICUs. A total of 1702 patients admitted between August 31, 2017 and February 16, 2019 were included. LUS was performed according to the bedside lung ultrasound in emergency (BLUE)-plus protocol, and LUS scores were calculated. Data on the outcomes and oxygenation indices were analyzed and compared between different primary indication groups.Results The LUS scores were significantly higher for non-survivors than for survivors and were significantly different between the oxygenation index groups, with higher scores in the lower oxygenation index groups. The LUS score was an independent risk factor for the 28-day mortality. The area under the receiver operating characteristic curve was 0.663 for prediction of the 28-day mortality and 0.748 for prediction of an oxygenation index