A Novel 5'-Iodonucleoside Allows Efficient Nonenzymatic Ligation of Single-stranded and Duplex DNAs.

A Novel 5'-Iodonucleoside Allows Efficient Nonenzymatic Ligation of Single-stranded and Duplex DNAs.
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新型 5-碘核苷可实现单链和双链 DNA 的高效非酶连接。

DOI:
10.1016/s0040-4039(97)01266-5
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发表时间:
1997
影响因子:
1.8
通讯作者:
Kool,EricT
Kool,EricT
中科院分区:
化学4区
文献类型:
--
作者:
Xu,Yanzheng;Kool,EricT

文献摘要

被引文献

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一种新的碘胸苷亚磷酰胺能够将5 '-碘化物置于寡核苷酸中;碘化物对氨脱保护稳定,并允许DNA的非酶连接。
A new iodothymidine phosphoramidite enables the placement of a 5'-iodide into oligonucleotides; the iodide is stable to ammonia deprotection and allows nonenzymatic ligations of DNA.