Coagulation disorders and the risk of retinal vein occlusion A subgroup analysis
Coagulation disorders and the risk of retinal vein occlusion A subgroup analysis
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DOI：
10.1160/th09-05-0331
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发表时间：
2010-02-01
影响因子：
6.7
通讯作者：
Hattenbach, Lars-Olof
中科院分区：
文献类型：
--
作者：
Kuhli-Hattenbach, Claudia;Scharrer, Inge;Hattenbach, Lars-Olof
在过去的几年里，血栓形成倾向的可识别原因数量急剧增加。然而，到目前为止，还没有大型的前瞻性研究来评估一种最佳的、具有成本效益的方法，用于筛查和发现视网膜血管阻塞患者的血栓形成风险因素。对228例视网膜静脉阻塞（RVO）患者和130例年龄匹配的健康对照者进行了前瞻性筛选，以确定是否存在血栓形成危险因素。根据RVO或既往血栓栓塞事件时患者的年龄，将两个队列分为三个亚组。病人年龄！45岁与凝血障碍的高患病率相关（p
Over the past years, there has been a dramatic increase in the number of identifiable causes of thrombophilia. However, to date, there are no large, prospective studies to assess an optimal, cost-effective approach with regard to screening and case finding for thrombophilic risk factors in patients presenting with retinal vessel occlusion. Two hundred twenty-eight patients with retinal vein occlusion (RVO) and 130 age-matched healthy controls were prospectively screened for thrombophilic risk factors. Both cohorts were divided into three subgroups, depending on the patients' age at the time of the RVO or a previous thromboembolic event. Patient age ! 45 years was associated with a high prevalence of coagulation disorders (p