Appropriate BMI levels for PCOS patients in Southern China
Appropriate BMI levels for PCOS patients in Southern China
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DOI：
10.1093/humrep/deq028
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发表时间：
2010-05-01
影响因子：
6.1
通讯作者：
Yang, Dongzi
中科院分区：
文献类型：
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作者：
Chen, Xiaoli;Ni, Renmin;Yang, Dongzi
通过对999例PCOS患者(857例成人和142例青少年)和922例年龄匹配的对照组(742例成年人和180例青少年)的临床横断面研究，发现BMI>23 kg/m(2)的PCOS患者所占比例为34.63%。PCOS患者血清胰岛素、甘油三酯、腰围、腰臀比(W/H)均与BMI呈正相关。中国PCOS患者代谢综合征患病率为18.9%。受试者操作特征分析显示，当BMI=23 kg/m(2)时，对代谢紊乱的诊断能力最强，BMI大于或等于23 kg/m(2)的PCOS患者发生代谢紊乱的风险较高。采用适当的体重指数水平可能有助于提高中国南部地区多囊卵巢综合征患者对代谢紊乱的关注。
This study was designed to establish appropriate body mass index (BMI) level for PCOS women and to compare metabolic abnormalities between PCOS women and control women in Southern China.This clinical cross-sectional study included 999 PCOS patients (857 adults and 142 adolescents) and 922 age-matched controls (742 adults and 180 adolescents).The proportion of PCOS patients with a BMI above 23 kg/m(2) was 34.63%. Serum insulin, triglycerides, waist and waist/hip (W/H) measurements were all correlated positively with BMI in PCOS women. Prevalence of metabolic syndrome in Chinese PCOS patients was 18.9%. Receiver-operating characteristic analysis suggested that at the point of BMI >= 23 kg/m(2), the diagnostic power to detect metabolic disorders was at its best.PCOS patients with a BMI of 23 kg/m(2) or beyond may have a higher risk of metabolic disorders. Using an appropriate BMI level may help to improve attention to metabolic disorders among PCOS patients in Southern China.