An expanded view of infertility: The challenge of the changing profiling of major birth defects in China
An expanded view of infertility: The challenge of the changing profiling of major birth defects in China
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DOI：
10.5582/bst.2023.01160
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发表时间：
2023-07-20
影响因子：
5.5
通讯作者：
Wang, Jianhua
中科院分区：
文献类型：
--
作者：
Chen, Zhongzhong;Wang, Yanlin;Wang, Jianhua
在过去的二十年里，中国经历了出生率的显著下降，同时伴随着生育率的下降和主要先天缺陷的变化。辅助生殖技术（ART）的发展为面临不孕症的个体带来了希望。然而，出现了一些与生殖健康和先天缺陷有关的问题。需要进一步调查出生缺陷特征变化的原因以及生育率下降与抗逆转录病毒疗法之间的关系。需要改变营养补充等生活方式因素，以保护生殖能力。出生缺陷，如先天性心脏病和尿道下裂，可以作为了解生育能力下降的信号。为了提高生育率，需要查明造成生育率的因素，需要引进重要的遗传和医疗技术，需要实施环境干预措施，如改变营养。
Over the past two decades, China has experienced a significant decline in birth rates, accompanied by a decrease in fertility and changes in major congenital defects. The development of assisted reproductive technology (ART) has brought hope to individuals facing infertility. However, some issues related to reproductive health and congenital defects have arisen. The reasons for the changing profiling of birth defects and the relationship between the decline in fertility and ART need to be further investigated. Lifestyle factors such as nutritional supplementation need to be altered to protect reproductive capacity. Birth defects, such as congenital heart defects and hypospadias, may serve as a signal for understanding the decline in fertility. To improve fertility, the factors contributing to it need to be identified, vital genetic and medical technologies need to be introduced, and environmental interventions, such as nutritional changes, need to be implemented.