Computational Comparison Between Newtonian and Non-Newtonian Blood Rheologies in Stenotic Vessels

Computational Comparison Between Newtonian and Non-Newtonian Blood Rheologies in Stenotic Vessels
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DOI:
10.1007/978-3-319-59548-1_10
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发表时间:
2018-01-01
期刊:
BIOMEDICAL TECHNOLOGY: MODELING, EXPERIMENTS AND SIMULATION
影响因子:
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通讯作者:
Vergara, Christian
Vergara, Christian
中科院分区:
其他
文献类型:
--
作者:
Guerciotti, Bruno;Vergara, Christian

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这项工作的目的是调查的影响,非牛顿血液流变学的3D患者特定的狭窄血管的血液动力学,通过比较的一些数值结果与牛顿的情况。特别是,我们考虑了两个颈动脉严重狭窄和狭窄的冠状动脉与旁路移植术治疗,我们几乎不同的狭窄程度。我们使用Carreau-Yasuda模型来描述非牛顿血液流变学的有限元方法的基础上进行非稳态数值模拟。我们的研究结果表明,在狭窄的颈动脉的情况下,速度,涡度和壁面剪应力分布的非牛顿模型的影响适度。另一方面,我们观察到,一个非牛顿模型似乎是重要的狭窄的冠状动脉的情况下,特别是计算的相对停留时间,这是很大程度上受流变模型。
This work aims at investigating the influence of non-Newtonian blood rheology on the hemodynamics of 3D patient-specific stenotic vessels, by means of a comparison of some numerical results with the Newtonian case. In particular, we consider two carotid arteries with severe stenosis and a stenotic coronary artery treated with a bypass graft, in which we virtually vary the degree of stenosis. We perform unsteady numerical simulations based on the Finite Element method using the Carreau-Yasuda model to describe the non-Newtonian blood rheology. Our results show that velocity, vorticity and wall shear stress distributions are moderately influenced by the non-Newtonian model in case of stenotic carotid arteries. On the other hand, we observed that a non-Newtonian model seems to be important in case of stenotic coronary arteries, in particular to compute the relative residence time which is greatly affected by the rheological model.