DIABETIC GASTROPARESIS FROM AUTONOMIC NEUROPATHY - SURGICAL CONSIDERATIONS AND CHANGES IN VAGUS NERVE MORPHOLOGY
DIABETIC GASTROPARESIS FROM AUTONOMIC NEUROPATHY - SURGICAL CONSIDERATIONS AND CHANGES IN VAGUS NERVE MORPHOLOGY
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DOI：
10.1136/jnnp.47.7.686
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发表时间：
1984-01-01
影响因子：
11
通讯作者：
WATKINS, PJ
中科院分区：
文献类型：
--
作者：
GUY, RJC;DAWSON, JL;WATKINS, PJ
本文描述了两例难治性呕吐，胃轻瘫是糖尿病自主神经病变的罕见特征。两人都需要手术治疗。在第一个病例中，胃肠造口术并发反流性胃炎，需要翻修手术；第二例胃空肠吻合术成功。其中一例迷走神经的电子显微镜研究显示，无髓鞘轴突的密度严重减少，存活的轴突趋向于小口径。这些异常的严重程度支持了糖尿病性胃轻瘫与迷走神经去支配有关的观点。
Two cases with intractable vomiting due to gastroparesis, a rare feature of diabetic autonomic neuropathy, are described. Both required surgical treatment. In the first a gastroenterostomy was complicated by reflux gastritis requiring a revision operation; in the second a gastrojejunostomy was successful. Electron microscopic studies of the vagus nerve in one of the cases showed a severe reduction in the density of unmyelinated axons, the surviving axons tending to be of small calibre. The severity of the abnormalities supports the view that diabetic gastroparesis is related to vagal denervation.