THE RELATIONSHIP BETWEEN PLASMA TRIGLYCERIDES, CHOLESTEROL, TOTAL LIPIDS AND LIPID-PEROXIDATION PRODUCTS DURING HUMAN ATHEROSCLEROSIS
THE RELATIONSHIP BETWEEN PLASMA TRIGLYCERIDES, CHOLESTEROL, TOTAL LIPIDS AND LIPID-PEROXIDATION PRODUCTS DURING HUMAN ATHEROSCLEROSIS
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DOI：
10.1016/0009-8981(86)90247-0
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发表时间：
1986-03-28
影响因子：
5
通讯作者：
KADZIOLKA, A
中科院分区：
文献类型：
--
作者：
LEDWOZYW, A;MICHALAK, J;KADZIOLKA, A
血浆甘油三酯，胆固醇，总脂质和脂质过氧化物的外周动脉粥样硬化病变的患者，谁被分为组根据病变的范围和强度的浓度进行了估计，以及在动脉壁的脂质过氧化物水平。与对照组相比，在所有组中发现估计化合物的统计学显著性增加。脂质过氧化物浓度和血浆中的其他成分之间存在正相关性，血浆中的脂质过氧化物水平和动脉壁中的脂质过氧化物水平之间存在正相关性，脂质过氧化物参与起源动脉粥样硬化病变的过程中可能的机制进行了讨论。
Concentrations of plasma triglycerides, cholesterol, total lipids and lipid peroxides in patients with atherosclerotic lesions of peripheral arteries, who were divided into groups according to the extent and intensity of the lesions, were estimated, as well as lipid peroxide levels in the arterial wall. Statistically highly significant increases of the estimated compounds were found in all groups in comparison with the controls. The existence of a positive correlation between the lipid peroxide concentration and other investigated components in plasma and between the lipid peroxide level in plasma and in the arterial wall was found. Possible mechanisms for lipid peroxide involvement in the process of originating atherosclerotic lesions are discussed.