Medical treatment of glaucoma - A reappraisal of the risks
Medical treatment of glaucoma - A reappraisal of the risks
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DOI：
10.1136/bjo.80.1.85
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发表时间：
1996-01-01
影响因子：
4.1
通讯作者：
Franks, W
中科院分区：
文献类型：
--
作者：
Diggory, P;Franks, W
近年来，越来越多的证据表明，在原发性开角型青光眼中，手术治疗在降低眼压和保留视野方面比滴眼剂更有效。2 反对青光眼初次手术的论点是进行眼内手术对眼睛造成的风险。局部药物治疗对整体健康（尤其是老年人）的风险被低估，对于需要治疗青光眼的患者来说，手术可能是更安全、更有效的选择。已证明对青光眼有效的唯一治疗方法是降低眼内压。滴眼剂是青光眼治疗的主要手段，因为它们是极好的降眼压药，且局部副作用很少，所以局部 1 拮抗剂是最常开处方的一类药物。 3 治疗是终生的，许多高龄人士接受治疗。眼科医生和老年科医生有许多共同的患者。开角型青光眼主要是一种老年疾病，到 65 岁为止，影响高达 5% 的人口，并且在老年人中变得更加常见。 4 5 呼吸系统和心血管疾病在这个年龄段也很常见，并且这两种疾病都可能受到治疗青光眼的眼药水的影响。
There has been an accumulation of evidence in recent years to demonstrate that surgical treatment is more effective than eyedrops at lowering intraocular pressure and preserving the visual field in primary open angle glaucoma.'2 The argument against primary surgery for glaucoma has been the risk to the eye of performing an intraocular operation. The risks of topical medical therapy to general health, particularly that of elderly people, have been underestimated and surgery is likely to be both a safer and a more effective option for patients requiring treat-ment for glaucoma.The only therapeutic approach to have proved effective in glaucoma is lowering intraocular pressure. Eyedrops are the mainstay of glaucoma treatment and, because they are excellent ocular hypotensives with few local side effects, topical 1 antagonists are the class of drug most often prescribed. 3 Therapy is life long and many people of extreme old age receive treatment. Ophthalmologists and geriatricians havemany patients in common. Open angle glaucoma is predominantly a disease of old age, affecting up to 5% of the population by 65 years and becoming even more common inolder age. 4 5 Respiratory and cardiovascular disease are also common in this age group and both may be affected by eyedrops prescribed for glaucoma.