Near infra-red interactance for nutritional assessment of dialysis patients
Near infra-red interactance for nutritional assessment of dialysis patients
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DOI：
10.1093/ndt/14.1.169
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发表时间：
1999-01-01
影响因子：
6.1
通讯作者：
Luft, FC
中科院分区：
文献类型：
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作者：
Kalantar-Zadeh, K;Dunne, E;Luft, FC
背景。营养不良是透析患者的常见问题，可能影响多达三分之一的患者。近红外相互作用 (NIR) 是一种估计身体成分和全身脂肪百分比的新方法。方法。我们使用近红外交互仪 (Futrex 5000(R)) 来估计身体成分，包括体脂百分比，以及主观整体评估 (SGA)、人体测量值，包括中臂围 (MAC)、三头肌和二头肌皮褶厚度、计算出的中臂肌肉围 (MAMC)、体重指数 (BMI) 和实验室值。透析结束后不久测量 NIR 评分、SGA 评估和人体测量参数。 NIR 测量是通过将 Futrex(R) 传感器放置在不可接近的上臂上几秒钟来进行的。还检测了血清白蛋白、转铁蛋白（通过总铁结合能力反映）和总胆固醇浓度。结果。从 120 名血液透析患者中选出 34 名患者（20 名男性和 14 名女性）。他们的年龄从 26 岁到 86 岁（58 +/- 14 岁）不等。透析时间范围为 8 个月至 19 年（4.5 +/- 4.6 年）。 NIR 评分在三个 SGA 组中存在显着差异：(A) 营养良好，32.5 +/- 6.9%；(A) 营养良好，32.5 +/- 6.9%； (B) 轻度至中度营养不良，29.2 +/- 5.3%； (C) 严重营养不良，23.2 +/- 10.2% (P < 0.001)。 NIR 评分与营养相关参数之间的皮尔逊相关系数 (r) 对于体重指数 (r = +0.81)、中臂周长 (r = +0.74)、三头肌皮褶 (r = +0.54)、二头肌皮褶 (r = +0.55) 和中臂肌肉周长 (r = +0.54) 显着 (P < 0.001)。 NIR 与透析年数之间还发现负相关（r = -0.49，P = 0.004），这表明根据 NIR，透析时间越长的患者体脂百分比越低。 NIR 与血清转铁蛋白 (r = + 0.41，P = 0.016) 和胆固醇 (r = +0.39，P = 0.022) 相关，与血清白蛋白有一定相关性 (r = +0.29，P = 0.097)。结论。我们的结论是，NIR 可在几秒钟内完成，可以作为血液透析患者营养状况的客观指标。需要更多的比较和纵向研究来证实近红外测量在透析患者营养评估中的有效性。
Background. Malnutrition is a common problem in dialysis patients and may affect up to one-third of patients. Near-infrared interactance (NIR) is a novel approach to estimate body composition and per cent total body fat.Methods. We used near-infrared interactance (Futrex 5000(R)) to estimate the body composition including body fat percentage, as well as subjective global assessment (SGA), anthropometric measurements including mid-arm circumference (MAC), triceps and biceps skinfold thickness, calculated mid-arm muscle circumference (MAMC), body mass index (BMI), and laboratory values. NIR score, SGA assessment and anthropometric parameters were measured shortly after the end of a dialysis session. NIR measurement was made by placing a Futrex(R) sensor on the non-access upper arm for several seconds. Serum albumin, transferrin (reflected by total iron binding capacity), and total cholesterol concentrations were performed as well.Results. Thirty-four patients (20 men and 14 women) were selected from a pool of 120 haemodialysis patients. Their ages ranged from 26 to 86 years (58 +/- 14 years). Time on dialysis ranged from 8 months to 19 years (4.5 +/- 4.6 years). NIR scores were significantly different in three SGA groups: (A) well-nourished, 32.5 +/- 6.9%; (B) mildly to moderately malnourished, 29.2 +/- 5.3%; and (C) severely malnourished, 23.2 +/- 10.2% (P < 0.001). Pearson correlation coefficients (r) between the NIR score and nutritionally relevant parameters were significant (P < 0.001) for body mass index (r = +0.81), mid-arm circumference (r = +0.74), triceps skin fold (r = +0.54), biceps skin fold (r = +0.55), and mid-arm muscle circumference (r = +0.54). An inverse correlation was also found between NIR and years dialysed (r = -0.49, P = 0.004), denoting a lesser body fat percentage according to NIR for patients dialysed longer. NIR was correlated with serum transferrin (r = + 0.41, P = 0.016) and cholesterol (r = +0.39, P = 0.022) and marginally with serum albumin (r = +0.29, P = 0.097).Conclusions. We conclude that NIR, which can be performed within seconds, may serve as an objective indicator of nutritional status in haemodialysis patients. More comparative and longitudinal studies are needed to confirm the validity of NIR measurements in nutritional evaluation of dialysis patients.