GENETIC STUDY OF VESICULAR STOMATITIS VIRUS - CLASSIFICATION OF SPONTANEOUS THERMOSENSITIVE MUTANTS IN COMPLEMENTATION GROUPS
GENETIC STUDY OF VESICULAR STOMATITIS VIRUS - CLASSIFICATION OF SPONTANEOUS THERMOSENSITIVE MUTANTS IN COMPLEMENTATION GROUPS
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DOI：
10.1099/0022-1317-8-3-187
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发表时间：
1970-01-01
影响因子：
3.8
通讯作者：
FLAMAND, A
中科院分区：
文献类型：
--
作者：
FLAMAND, A
L'isolement de mutants spontanés thermosensibles a permis d'entreprendre l'étude génétique du Virus de la Stomatite Vésiculaire.这些突变体在鸡的成纤维细胞带上有30°的板，但迈斯不是39.8 ± 0.2°。本文报告了5组71种突变体的互补试验结果。分离出71种水泡性口炎病毒的自发性温敏突变体，并进行了互补试验。自发突变率似乎非常高，因为在野生型克隆中发现了2.3%的突变体。实验在30°（允许温度）和39.8°（非允许温度）下进行。突变体可分为五个互补组。58个突变体属于第一组。
L’isolement de mutants spontanés thermosensibles a permis d’entreprendre l’étude génétique du Virus de la Stomatite Vésiculaire. Ces mutants donnent des plages à 30° sur un tapis de fibroblastes de poulet mais n’en donnent pas à 39.8 ± 0.2°. Cet article rapporte le résultat de tests de complémentation conduisant à classer 71 mutants en 5 groupes.Seventy-one spontaneous thermosensitive mutants of Vesicular Stomatitis Virus were isolated and tested for complementation. The spontaneous mutation rate seems to be very high since 2.3% of mutants were found in wild-type clones. Experiments were performed at 30° (permissive temperature) and 39.8° (non-permissive temperature). The mutants can be classified into five complementation groups. 58 mutants fall into the first group.