Broadband cavity-enhanced absorption spectroscopy for real time, in situ spectral analysis of microfluidic droplets
Broadband cavity-enhanced absorption spectroscopy for real time, in situ spectral analysis of microfluidic droplets
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DOI：
10.1039/c1lc20854c
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发表时间：
2011-01-01
期刊：
影响因子：
6.1
通讯作者：
Mackenzie, Stuart R.
中科院分区：
文献类型：
--
作者：
Neil, Simon R. T.;Rushworth, Cathy M.;Mackenzie, Stuart R.
宽带腔增强吸收光谱已被用于真实的时间记录微流控芯片组件内微升体积水相液滴的吸收光谱。使用超连续谱辐射和宽带涂层外反射镜，以高重复率（273 Hz/3.66 ms采集时间）和高灵敏度（α（min）< 10（-2）cm（-1））原位采集每个经过的液滴的全可见光谱（430 nm < lambda < 700 nm）。讨论了使用定制设计的芯片进一步提高灵敏度和采集速率的可能性。
Broadband cavity-enhanced absorption spectroscopy has been used to record, in real time, the absorption spectrum of microlitre volume aqueous phase droplets within a microfluidic chip assembly. Using supercontinuum radiation and broadband coated external mirrors, the full visible spectrum (430 nm < lambda < 700 nm) of each passing droplet is acquired in situ at high repetition rates ( 273 Hz/3.66 ms acquisition time) and high sensitivity (alpha(min) < 10(-2) cm(-1)). The possibilities for further improvements in sensitivity and acquisition rate using custom designed chips are discussed.