Tryptophan 2, 3-dioxygenase promotes proliferation, migration and invasion of ovarian cancer cells

Tryptophan 2, 3-dioxygenase promotes proliferation, migration and invasion of ovarian cancer cells
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色氨酸2,3-双加氧酶促进卵巢癌细胞增殖、迁移和侵袭

DOI:
10.3892/mmr.2021.12084
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发表时间:
2021-04
影响因子:
3.4
通讯作者:
Tang Kai-Fu
Tang Kai-Fu
中科院分区:
医学4区
文献类型:
--
作者:
Zhao Yuemei;Tao Fengxing;Jiang Jiayu;Chen Lina;Du Jizao;Cheng Xiaoxiao;He Qin;Zhong Shouhui;Chen Wei;Wu Xiaoli;Ou Rongying;Xu Yunsheng;Tang Kai-Fu

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Tryptophan 2,3-dioxygenase (TDO2) is a key rate-limiting enzyme in the kynurenine pathway and promotes tumor growth and escape from immune surveillance in different types of cancer. The present study aimed to investigate whether TDO2 serves a role in the
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