Copper(II)-catalyzed three-component cascade annulation of diaryliodoniums, nitriles, and alkynes: a regioselective synthesis of multiply substituted quinolines.

Copper(II)-catalyzed three-component cascade annulation of diaryliodoniums, nitriles, and alkynes: a regioselective synthesis of multiply substituted quinolines.
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DOI:
10.1002/anie.201300586
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发表时间:
2013-05
期刊:
影响因子:
--
通讯作者:
Yong Wang;Chao Chen;Jing Peng;Ming Li
Yong Wang;Chao Chen;Jing Peng;Ming Li
中科院分区:
--
文献类型:
--
作者:
Yong Wang;Chao Chen;Jing Peng;Ming Li

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利用Cu(II)催化的二芳基碘鎓离子、腈和炔的三组分[2 + 2 + 2]环缩合反应,以二芳基碘鎓的芳基作为C2构建单元,研究了多种取代喹啉的区域选择性合成。
A regioselective synthesis of a variety of substituted quinolines is developed using a Cu(II)-catalyzed three-component [2 + 2 + 2] cyclocondensation of diaryliodonium ions, nitriles, and alkynes, whereat the aryl group of the diaryliodonium serves as a C2 building block.