Digital Tomosynthesis in breast imaging
Digital Tomosynthesis in breast imaging
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DOI：
10.1148/radiology.205.2.9356620
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发表时间：
1997-11-01
期刊：
影响因子：
19.7
通讯作者：
Wirth, RF
中科院分区：
文献类型：
--
作者：
Niklason, LT;Christian, BT;Wirth, RF
目的：描述和评价一种采用全视野数字乳房x线摄影系统的断层合成乳房成像方法。材料和方法：在这种断层合成方法中，当x射线源在静止乳房和数字探测器上方移动时，获得低辐射剂量图像。采用阶梯曝光成像方法。获得2个成像幻影和4个乳房切除术标本的乳腺断层合成和常规图像。三名经验丰富的读者对病灶的相对可见性、病灶边缘可见性和对六个病灶分类的信心进行了评分。结果：层析合成图像重建算法允许从单个x射线源和辐射剂量与单视图乳房x线摄影相当的整个乳房的层析成像。除脂肪性乳房肿块外，断层合成图像优于常规图像。结论：数字化乳房x线摄影系统使乳腺层析成像成为可能。层析合成可以提高乳房x线摄影的特异性，提高病变边缘的可见性，并可以提高早期乳腺癌的检测，特别是在放射学上致密乳房的女性中。
PURPOSE: To describe and evaluate a method of tomosynthesis breast imaging with a full-field digital mammographic system.MATERIALS AND METHODS: In this tomosynthesis method, low-radiation-dose images were acquired as the x-ray source was moved in an are above the stationary breast and digital detector. A step-and-expose method of imaging was used. Breast tomosynthesis and conventional images of two imaging phantoms and four mastectomy specimens were obtained. Three experienced readers scored the relative lesion visibility, lesion margin visibility, and confidence in the classification of six lesions.RESULTS: Tomosynthesis image-reconstruction algorithms allow tomographic imaging of the entire breast from a single are of the x-ray source and at a radiation dose comparable with that in single-view mammography. Except for images of a large mass in a fatty breast, the tomosynthesis images were superior to the conventional images.CONCLUSION: Digital mammographic systems make breast tomosynthesis possible. Tomosynthesis may improve the specificity of mammography with improved lesion margin visibility and may improve early breast cancer detection, especially in women with radiographically dense breasts.