Low Bone Mineral Density Is Not Associated with Subclinical Atherosclerosis: A Population-Based Study in Rural China
Low Bone Mineral Density Is Not Associated with Subclinical Atherosclerosis: A Population-Based Study in Rural China
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DOI：
10.1159/000493166
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发表时间：
2018-01-01
期刊：
影响因子：
1.9
通讯作者：
Chen, Xingdong
中科院分区：
文献类型：
--
作者：
Jiang, Yanfeng;Fan, Zehan;Chen, Xingdong
目的：骨量丢失可能影响动脉粥样硬化的进展。我们调查了中国农村低骨密度与亚临床动脉粥样硬化的关系。方法：共纳入333名男性和421名绝经后女性，年龄55-65岁。采用双能X线骨密度仪测量腰椎、股骨颈和全髋部的骨密度。亚临床动脉粥样硬化的定义是颈动脉内膜厚度增加(CIMT和>T；=0.9 mm)，颈动脉斑块的存在，高的臂踝-踝脉搏波速度(BaPWV和>T；=1,400 cm/S)，和低的踝臂指数(ABI
Objectives: Loss of bone mass may affect the progression of atherosclerosis. We investigated the relationship between low bone mineral density (BMD) and subclinical atherosclerosis in rural China. Methods: In total, 333 men and 421 postmenopausal women aged 55-65 years were enrolled. BMD was measured in the lumbar spine, femoral neck, and total hip using dual-energy X-ray absorptiometry. Subclinical atherosclerosis was defined as increased carotid artery intimamedia thickness (CIMT >= 0.9 mm), the presence of carotid plaques, high brachial-ankle pulse wave velocity (baPWV >= 1,400 cm/s), and low ankle-brachial index (ABI