The incidence of frontotemporal lobar degeneration in Rochester, Minnesota, 1990 through 1994
The incidence of frontotemporal lobar degeneration in Rochester, Minnesota, 1990 through 1994
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DOI：
10.1212/01.wnl.0000106827.39764.7e
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发表时间：
2004-02-10
期刊：
影响因子：
9.9
通讯作者：
Rocca, WA
中科院分区：
文献类型：
--
作者：
Knopman, DS;Petersen, RC;Rocca, WA
罗切斯特流行病学项目的记录链接系统用于查明 1990 年至 1994 年明尼苏达州罗切斯特市发生的额颞叶变性 (FTLD) 病例。确定了 4 例 FTLD 病例（均为女性）；其中两人经神经病理学证实。所有患者均属于行为执行障碍型，发病年龄在 70 岁之前。40 至 49 岁的发病率（每 10 万人年新发病例）为 2.2，50 至 59 岁为 3.3，60 至 69 岁为 8.9。作为比较，阿尔茨海默病的相应发病率为 0.0、3.3 和 88.9。
The records-linkage system of the Rochester Epidemiology Project was used to ascertain incident cases of frontotemporal lobar degeneration (FTLD) in Rochester, MN, from 1990 through 1994. Four cases of FTLD were identified (all women); two were confirmed neuropathologically. All were of the behavioral-dysexecutive type and had onset before age 70. The incidence rates (new cases per 100,000 person-years) were 2.2 for ages 40 to 49, 3.3 for ages 50 to 59, and 8.9 for ages 60 to 69. For comparison, the corresponding rates for Alzheimer disease were 0.0, 3.3, and 88.9.