EFFERENT CONNECTIONS OF THE ROSTRAL PORTION OF MEDIAL AGRANULAR CORTEX IN RATS
EFFERENT CONNECTIONS OF THE ROSTRAL PORTION OF MEDIAL AGRANULAR CORTEX IN RATS
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DOI：
10.1016/0361-9230(87)90086-4
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发表时间：
1987-08-01
影响因子：
3.8
通讯作者：
WATSON, RT
中科院分区：
文献类型：
--
作者：
REEP, RL;CORWIN, JV;WATSON, RT
这项针对内侧无颗粒皮质 (AGm) 嘴侧部分的研究有两个主要目标。首先，描述 AGm 的传出连接，并将其与我们在之前的研究中定义的传入模式进行比较。其次，为与猴子皮质区域的解剖和功能比较提供更坚实的基础。使用放射自显影、辣根过氧化物酶和纤维变性技术。喙端 AGm 具有多种皮质连接。sbd.与外侧无颗粒运动皮层 (AG)；视觉、听觉和躯体感觉区域；边缘/旁边缘区域，包括眼眶、岛叶、鼻周、内嗅、压后和皮下区。眼眶、鼻周和内嗅皮质的投射是双侧的。喙侧 AGm 的丘脑投射集中在腹外侧核、中央外侧核、旁中央核、背内侧核和腹内侧核。在网状核、前内侧核、中央内侧核、胶质细胞核、束旁核和后核中一致可见中等末端野。更多尾部投射到达中央灰质、上丘和脑桥灰质。还检查了相邻 AG1 的传出神经。尽管其中许多与吻侧 AGm 重叠，但没有视觉或听觉皮层的传出，边缘/旁边缘投射减少。丘脑投射更集中在腹侧外侧核和后核，并且在中央灰质或上丘中没有终端区域。基于其传入和传出连接、对侧忽视的作用以及微刺激研究的结果，喙侧 AGm 可以被视为与运动系统具有紧密联系的多模式关联区域。在这些结构和功能基础上，喙 AGm 与猴子皮层的额眼区、辅助运动区和弓形前运动区具有某些惊人的相似之处。
This study of the rostral part of medial agranular cortex (AGm) was undertaken with two principal aims in mind. First, to delineate the efferent connections of AGm and compare these with the pattern of afferents defined by us in a previous study. Second, to provide a firmer basis for anatomical and functional comparisons with cortical regions in monkeys. Autoradiographic, horseradish peroxidase, and fiber degeneration techniques were used. Rostral AGm has a variety of corticocortical connections.sbd.with lateral agranular motor cortex (AG); visual, auditory, and somatic sensory regions; and limbic/paralimbic areas including orbital, insular, perirhinal, entorhinal, retrosplenial and presubicular fields. The projections to orbital, perirhinal and entorhinal cortices are bilateral. Thalamic projections of rostral AGm are concentrated in the ventral lateral, central lateral, paracentral, mediodorsal and ventromedial nuclei. Moderate terminal fields are consistently seen in the reticular, anteromedial, central medial, gelatinosus, parafascicular, and posterior nuclei. More caudal projections reach the central gray, superior colliculus and pontine gray. The efferents of the adjacent AGl were also examined. Although many of these overlapped those of rostral AGm, there were no efferents to visual or auditory cortex and limbic/paralimbic projections were reduced. Thalamic projections were more focused in the ventral lateral and posterior nuclei and there were no terminal fields in the central gray or superior colliculus. Based on its afferent and efferent connections, role in contralateral neglect, and the results of microstimulation studies, rostral AGm can be viewed as a multimodal association area with strong ties to the motor system. On these structural and functional grounds, rostral AGm bears certain striking resemblances to the frontal eye field, supplementary motor, and arcuate premotor areas of monkey cortex.