SUSCEPTIBILITY OF PNEUMOCOCCI TO 9 ANTIBIOTICS
SUSCEPTIBILITY OF PNEUMOCOCCI TO 9 ANTIBIOTICS
复制标题
DOI：
10.1097/00000441-196509000-00003
复制
发表时间：
1965-01-01
影响因子：
3.1
通讯作者：
FINLAND, M
中科院分区：
文献类型：
--
作者：
KISLAK, JW;RAZAVI, LMB;FINLAND, M
对波士顿市立医院分离的200株肺炎球菌进行了体外青霉素G、红霉素、四环素、萘夫西林和苯唑西林敏感性试验。还对这些菌株中的73株进行了头孢菌素试验。此外，还对43种其他菌株进行了氨苄青霉素试验。氯唑西林组32例，头孢噻吩组41例。血清型有24种，其中3型、19型、14型、6型和8型占半数以上。体外抗菌活性依次为红霉素、青霉素G、头孢啶、氨苄西林、萘夫西林、苯唑西林、头孢噻吩、氯唑西林和四环素。作者强调，最近报道的对四环素耐药的肺炎球菌表明需要监测它们的抗生素敏感性。红霉素被推荐为青霉素过敏的首选药物。B。卢德拉姆
200 strains of pneumococci isolated in the Boston City Hospital were tested forin vitrosensitivity to penicillin G, erythromycin, tetracycline, nafcillin and oxacillin. 73 of these strains were also tested against cephaloridine. In addition 43 other strains were tested against ampicillin,. 32 against cloxacillin and 41 against cephalothin. 24 capsular serological types were represented, more than half being types 3, 19, 14, 6 or 8.No strains were resistant to any of the 9 antibiotics. The order ofin vitroactivity was erythromycin (the most active), penicillin G, cephaloridine, ampicillin, nafcillin, oxacillin, cephalothin, cloxacillin and tetracycline.The authors emphasize that recent reports of tetracycline-resistant pneumococci indicate the need for surveillance of their antibiotic sensitivity. Erythromycin is recommended as the drug of choice in the presence of allergy to penicillin.G. B. Ludlam.