Autonomic function assessed by heart rate variability is normal in Alzheimer's disease and vascular dementia
Autonomic function assessed by heart rate variability is normal in Alzheimer's disease and vascular dementia
复制标题
DOI：
10.1159/000082885
复制
发表时间：
2005-01-01
影响因子：
2.4
通讯作者：
Kenny, RA
中科院分区：
文献类型：
--
作者：
Allan, LM;Kerr, SRJ;Kenny, RA
心率变异性（HRV）是一种敏感的方法，用于评估自主神经功能，并需要很少的合作，从主题，使其适用于痴呆症。初步研究表明，HRV可能在阿尔茨海默病（AD）中受损。HRV尚未在血管性痴呆（VAD）中进行研究。我们研究自主神经功能的AD和VAD，使用功率谱分析的HRV。对114名参与者进行了评价（14名AD，20名VAD和80名对照）。受试者取仰卧位，记录静息心电图5分钟。根据国际HRV指南，功率谱分析用于获得极低频（<0.04 Hz）、低频（0.04 - 0.15 Hz）和高频（0.15 - 0.40 Hz）频带中的谱带和总谱功率（<0.40 Hz）。与对照组相比，AD或VAD患者的HRV无差异。版权所有（C）2005 S. Karger AG，巴塞尔。
Heart rate variability (HRV) is a sensitive method for the assessment of autonomic function and requires little cooperation from the subject, making it suitable for use in dementia. Preliminary studies have suggested that HRV may be impaired in Alzheimer's disease ( AD). HRV has not been studied in vascular dementia (VAD). We investigate autonomic function in AD and VAD, using power spectral analysis of HRV. One hundred and fourteen participants were evaluated ( 14 AD, 20 VAD and 80 controls). The resting ECG was recorded for 5 min with participants in the supine position. Power spectral analysis used to obtain spectral bands in the very-low- frequency (< 0.04 Hz), low- frequency ( 0.04 - 0.15 Hz) and high-frequency (0.15 - 0.40 Hz) bands and total spectral power (< 0.40 Hz) according to international HRV guidelines. There were no differences in HRV in patients with AD or VAD when compared with controls. Copyright (C) 2005 S. Karger AG, Basel.