Tissue engineering and developmental biology: Going biomimetic
Tissue engineering and developmental biology: Going biomimetic
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DOI：
10.1089/ten.2006.12.3265
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发表时间：
2006-12-01
影响因子：
--
通讯作者：
Vunjak-Novakovic, Gordana
中科院分区：
文献类型：
--
作者：
Ingber, Donald E.;Mow, Van C.;Vunjak-Novakovic, Gordana
这篇文章包含了在“组织工程--下一代”研讨会的第一次会议上发表的集体观点，该研讨会致力于发育生物学和组织工程之间的相互作用。唐纳德·英格伯从一位细胞生物学家的角度讨论了发育生物学和组织工程之间的鸿沟，他从早期就对组织工程感兴趣。作为最早涉足该领域的工程师之一，范·C·莫分享了组织工程学发展的历史观点。大卫·巴特勒对功能组织工程进行了评估，这是他帮助建立和推动的一个新领域。劳拉·尼克尔森讨论了如何更有效地为大量患者开发细胞疗法。约翰尼·胡德描述了他的组织工程方法，这种方法基于肌肉来源细胞的使用。杰里米·毛专注于天然发育和与组织工程相关的细胞归巢和细胞密度。Ioannis Yannas提出了一套器官再生的“规则”。全体教员表达了弥合发育生物学和组织工程之间差距的非凡热情，并就如何促进这两个领域之间的互动提出了新的想法。
This article contains the collective views expressed at the first session of the workshop "Tissue Engineering - The Next Generation,'' which was devoted to the interactions between developmental biology and tissue engineering. Donald Ingber discussed the chasms between developmental biology and tissue engineering from the perspective of a cell biologist who has had interest in tissue engineering since its early days. Van C. Mow shared a historical perspective on the development of tissue engineering as one of the first engineers involved in the field. David Butler offered an assessment of functional tissue engineering, a new area he helped establish and promote. Laura Niklason discussed how to be more effective in developing cellular therapies for large numbers of patients. Johnny Huard described his approach to tissue engineering, based on the use of muscle-derived cells. Jeremy Mao focused on cell homing and cell density in the context of native development and relevance to tissue engineering. Ioannis Yannas proposed a set of "rules'' in organ regeneration. Collectively, the faculty expressed a remarkable level of enthusiasm for bridging the gaps between developmental biology and tissue engineering and offered new ideas on how to facilitate the interaction between the two fields.