Healthcare-Associated Pertussis Outbreak in Arizona: Challenges and Economic Impact, 2011.
Healthcare-Associated Pertussis Outbreak in Arizona: Challenges and Economic Impact, 2011.
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亚利桑那州与医疗保健相关的百日咳疫情：挑战和经济影响，2011 年。
DOI：
10.1093/jpids/pis136
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发表时间：
2014
影响因子：
3.2
通讯作者：
R. Klein
中科院分区：
文献类型：
--
作者：
S. Yasmin;R. Sunenshine;K. Bisgard;Caleb Wiedeman;A. Carrigan;T. Sylvester;Greg Garcia;Karen Rose;S. Wright;S. Miller;R. D. Huerta;Helen J. Houser;Aarikha D’Souza;S. Anderson;K. Howard;K. Komatsu;R. Klein
一项暴发调查在1家医院的新生儿重症监护室（NICU）的5名婴儿和10名医护人员中发现了15例百日咳病例。这次爆发给这家医院造成的损失是97745美元。在NICU中提高对百日咳的认识是预防医疗保健相关传播和最大限度地减少暴发控制相关成本的关键。百日咳杆菌是一种高度传染性的细菌病原体，可引起长期咳嗽疾病，并通过呼吸道飞沫传播。年龄≤6个月的婴儿最易感染B型百日咳和百日咳相关并发症，包括肺炎、脑病和死亡，通常住院治疗[ 1]。尽管有一个普遍的百日咳疫苗接种计划，但2010年美国报告了27550例百日咳病例[ 2]。在医疗机构中爆发百日咳可能具有挑战性，控制成本高昂[3]。2011年9月13日和2011年9月15日，B医院（一家大型儿科机构）向Marvila县公共卫生部报告了3例百日咳病例，其中包括2例经B型百日咳隔离确认的病例，这些病例发生在一家综合医院（NICU A）71张床位的NICU出院≤30天的早产儿中。本报告描述了疫情，审查了可能导致医疗相关传播的疫情相关成本和风险因素，并提供了预防医疗机构疫情的指导。
An outbreak investigation identified 15 pertussis cases among 5 infants and 10 healthcare professionals at 1 hospital's neonatal intensive care unit (NICU). The cost of the outbreak to this hospital was $97 745. Heightened awareness of pertussis in NICUs is key to preventing healthcare-associated spread and minimizing outbreak-control-related costs. Bordetella pertussis is a highly communicable bacterial pathogen that causes a prolonged cough illness and is spread by respiratory droplet transmission. Infants aged ≤6 months are most susceptible to B pertussis infection and pertussis-associated complications, including pneumonia, encephalopathy, and death, and are commonly hospitalized for treatment [ 1]. Despite a universal pertussis vaccination program, 27 550 pertussis cases were reported in the United States during 2010 [ 2]. Pertussis outbreaks in healthcare settings can be challenging and costly to control [3]. On September 13, 2011 and September 15, 2011, 3 pertussis cases, including 2 confirmed by B pertussis isolation, among preterm infants discharged ≤30 days previously from a 71-bed NICU of a general hospital (NICU A) were reported by Hospital B, a large pediatric facility, to Maricopa County Department of Public Health. This report describes the outbreak, examines outbreak-associated costs and risk factors that might have contributed to healthcare-associated transmission, and provides guidance to prevent outbreaks in healthcare settings.