Evolutionary Analysis of MIKC(c)-Type MADS-Box Genes in Gymnosperms and Angiosperms.
Evolutionary Analysis of MIKC(c)-Type MADS-Box Genes in Gymnosperms and Angiosperms.
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裸子植物和被子植物 MIKCc 型 MADS-Box 基因的进化分析
DOI：
10.3389/fpls.2017.00895
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发表时间：
2017
影响因子：
5.6
通讯作者：
Zhang L
中科院分区：
文献类型：
--
作者：
Chen F;Zhang X;Liu X;Zhang L
mikcc型MADS-box基因编码控制开花植物花器官形态发生和开花时间的转录因子。为了确定MIKCc亚科的起源时间及其早期进化轨迹，我们对裸子植物和基被子植物所有目的基因组和大尺度转录组进行了采样和分析。通过系统发育推断，将mikcc型MADS-box基因细分为14个单系支系。其中，鉴定出了AGL6、SEP、AP1、GMADS、SOC1、AGL32、AP3/PI、SVP、AGL15、ANR1和AG的裸子直系同源基因。我们在裸子植物中鉴定并鉴定了一个新的GMADS亚科的起源，但在单子叶植物和芸苔科中失去了同源植物。ABCE模型原型基因在裸子植物中相对保守，但在被子植物中扩增，而SVP、SOC1和GMADS在裸子植物中扩增明显，但在被子植物中保守。我们的研究结果提供了裸子植物和被子植物中所有MIKCc基因分支最详细的进化历史。我们认为，虽然裸子植物已经进化出了接近完整的MIKCc基因，但ABCE模式MIKCc基因在被子植物祖先中的复制和表达转变触发了第一朵花的形成。
MIKCc-type MADS-box genes encode transcription factors that control floral organ morphogenesis and flowering time in flowering plants. Here, in order to determine when the subfamilies of MIKCc originated and their early evolutionary trajectory, we sampled and analyzed the genomes and large-scale transcriptomes representing all the orders of gymnosperms and basal angiosperms. Through phylogenetic inference, the MIKCc-type MADS-box genes were subdivided into 14 monophyletic clades. Among them, the gymnosperm orthologs of AGL6, SEP, AP1, GMADS, SOC1, AGL32, AP3/PI, SVP, AGL15, ANR1, and AG were identified. We identified and characterized the origin of a novel subfamily GMADS within gymnosperms but lost orthologs in monocots and Brassicaceae. ABCE model prototype genes were relatively conserved in terms of gene number in gymnosperms, but expanded in angiosperms, whereas SVP, SOC1, and GMADS had dramatic expansions in gymnosperms but conserved in angiosperms. Our results provided the most detailed evolutionary history of all MIKCc gene clades in gymnosperms and angiosperms. We proposed that although the near complete set of MIKCc genes had evolved in gymnosperms, the duplication and expressional transition of ABCE model MIKCc genes in the ancestor of angiosperms triggered the first flower.