Recent development of ionic liquid stationary phases for liquid chromatography
Recent development of ionic liquid stationary phases for liquid chromatography
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液相色谱用离子液体固定相的最新进展
DOI：
10.1016/j.chroma.2015.09.090
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发表时间：
2015
影响因子：
4.1
通讯作者：
Xu Guowang
中科院分区：
文献类型：
--
作者：
Shi Xianzhe;Qiao Lizhen;Xu Guowang
离子液体以其独特的物理化学性质在分析化学的许多领域得到了广泛的应用。离子液体固定在硅胶或整体柱等载体上作为液相色谱固定相的种类很多。此外，开发了不同的方法将离子液体共价键合到支撑材料上。所制备的离子液体固定相具有多模式作用机理，包括疏水作用、亲水作用、氢键作用、阴离子交换作用、π-π作用和偶极-偶极作用。因此，它们可以用于不同的色谱模式，包括离子交换，RPLC，NPLC和HILIC分离各种类型的化合物。本文主要综述了近五年来离子液体固定相的固定方式、类型、保留机理及其应用。
Based on their particular physicochemical characteristics, ionic liquids have been widely applied in many fields of analytical chemistry. Many types of ionic liquids were immobilized on a support like silica or monolith as stationary phases for liquid chromatography. Moreover, different approaches were developed to bond covalently ionic liquids onto the supporting materials. The obtained ionic liquid stationary phases show multi-mode mechanism including hydrophobic, hydrophilic, hydrogen bond, anion exchange, π–π, and dipole–dipole interactions. Therefore, they could be used in different chromatographic modes including ion-exchange, RPLC, NPLC and HILIC to separate various classes of compounds. This review mainly summarizes the immobilized patterns and types of ionic liquid stationary phases, their retention mechanisms and applications in the recent five years.