Evaluation of Ultrasonic Fiber Structure Extraction Technique Using Autopsy Specimens of Liver
Evaluation of Ultrasonic Fiber Structure Extraction Technique Using Autopsy Specimens of Liver
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DOI：
10.1143/jjap.44.4615
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发表时间：
2005-06
影响因子：
1.5
通讯作者：
Tadashi Yamaguchi;Kazuki Hirai;H. Yamada;M. Ebara;H. Hachiya
中科院分区：
文献类型：
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作者：
Tadashi Yamaguchi;Kazuki Hirai;H. Yamada;M. Ebara;H. Hachiya
无创、准确诊断肝硬化具有重要意义。在我们以前的研究中，我们提出了一种处理技术来检测体内肝组织的变化。在本文中，我们提出了评估肝脏疾病和回声信息之间的关系，使用人体肝脏的尸检标本在体外。通过体外实验可以清楚地验证处理参数的功能，并将处理结果与实际人体肝脏组织结构进行比较。在我们的处理技术的结果中，根据特定处理参数的变化从尸检肝脏标本的回波信号中提取不服从瑞利分布的信息。从染色组织的许多组织学图像中提取相同标本的纤维组织结构。我们使用从回波信号和染色组织的纤维结构中提取的信息构建3D结构，并将两者进行比较。通过比较3D结构，可以评估不服从回波信号的瑞利分布的信息与纤维化结构之间的关系。
It is very important to diagnose liver cirrhosis noninvasively and correctly. In our previous studies, we proposed a processing technique to detect changes in liver tissue in vivo. In this paper, we propose the evaluation of the relationship between liver disease and echo information using autopsy specimens of a human liver in vitro. It is possible to verify the function of a processing parameter clearly and to compare the processing result and the actual human liver tissue structure by in vitro experiment. In the results of our processing technique, information that did not obey a Rayleigh distribution from the echo signal of the autopsy liver specimens was extracted depending on changes in a particular processing parameter. The fiber tissue structure of the same specimen was extracted from a number of histological images of stained tissue. We constructed 3D structures using the information extracted from the echo signal and the fiber structure of the stained tissue and compared the two. By comparing the 3D structures, it is possible to evaluate the relationship between the information that does not obey a Rayleigh distribution of the echo signal and the fibrosis structure.