The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation.
The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation.
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DOI：
10.1186/s12985-022-01923-x
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发表时间：
2022-12-15
期刊：
影响因子：
4.8
通讯作者：
Zhao, Zhongming
中科院分区：
文献类型：
--
作者：
Liu, Wendao;Ye, Xiaohua;An, Zhiqiang;Zhao, Zhongming
单细胞RNA测序在COVID-19研究中的应用，极大地提高了我们对COVID-19发病机制和免疫学特性的认识。在这篇评论中，我们讨论了利用单细胞RNA测序的力量加速COVID-19和其他新发传染病的基础研究和治疗开发的当前挑战、限制和前景。
The application of single-cell RNA sequencing in COVID-19 research has greatly improved our understanding of COVID-19 pathogenesis and immunological characteristics. In this commentary, we discuss the current challenges, limitations, and perspectives in harnessing the power of single-cell RNA sequencing to accelerate both basic research and therapeutic development for COVID-19 and other emerging infectious diseases.
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影响因子：
17.1
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Speranza E;Williamson BN;Feldmann F;Sturdevant GL;Pérez-Pérez L;Meade-White K;Smith BJ;Lovaglio J;Martens C;Munster VJ;Okumura A;Shaia C;Feldmann H;Best SM;de Wit E
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de Wit E
地塞米松调节严重的Covid-19中未成熟的中性粒细胞和干扰素编程。
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82.9
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Sinha S;Rosin NL;Arora R;Labit E;Jaffer A;Cao L;Farias R;Nguyen AP;de Almeida LGN;Dufour A;Bromley A;McDonald B;Gillrie MR;Fritzler MJ;Yipp BG;Biernaskie J
通讯作者：
Biernaskie J
影响因子：
64.8
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Delorey TM;Ziegler CGK;Heimberg G;Normand R;Yang Y;Segerstolpe Å;Abbondanza D;Fleming SJ;Subramanian A;Montoro DT;Jagadeesh KA;Dey KK;Sen P;Slyper M;Pita-Juárez YH;Phillips D;Biermann J;Bloom-Ackermann Z;Barkas N;Ganna A;Gomez J;Melms JC;Katsyv I;Normandin E;Naderi P;Popov YV;Raju SS;Niezen S;Tsai LT;Siddle KJ;Sud M;Tran VM;Vellarikkal SK;Wang Y;Amir-Zilberstein L;Atri DS;Beechem J;Brook OR;Chen J;Divakar P;Dorceus P;Engreitz JM;Essene A;Fitzgerald DM;Fropf R;Gazal S;Gould J;Grzyb J;Harvey T;Hecht J;Hether T;Jané-Valbuena J;Leney-Greene M;Ma H;McCabe C;McLoughlin DE;Miller EM;Muus C;Niemi M;Padera R;Pan L;Pant D;Pe'er C;Pfiffner-Borges J;Pinto CJ;Plaisted J;Reeves J;Ross M;Rudy M;Rueckert EH;Siciliano M;Sturm A;Todres E;Waghray A;Warren S;Zhang S;Zollinger DR;Cosimi L;Gupta RM;Hacohen N;Hibshoosh H;Hide W;Price AL;Rajagopal J;Tata PR;Riedel S;Szabo G;Tickle TL;Ellinor PT;Hung D;Sabeti PC;Novak R;Rogers R;Ingber DE;Jiang ZG;Juric D;Babadi M;Farhi SL;Izar B;Stone JR;Vlachos IS;Solomon IH;Ashenberg O;Porter CBM;Li B;Shalek AK;Villani AC;Rozenblatt-Rosen O;Regev A
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Regev A
影响因子：
32.1
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Liu, Wendao;Jia, Johnathan;Dai, Yulin;Chen, Wenhao;Pei, Guangsheng;Yan, Qiheng;Zhao, Zhongming
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Zhao, Zhongming
影响因子：
64.5
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Heath JR