Autochthonous Crimean-Congo Hemorrhagic Fever in Spain
Autochthonous Crimean-Congo Hemorrhagic Fever in Spain
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DOI：
10.1056/nejmoa1615162
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发表时间：
2017-07-13
影响因子：
158.5
通讯作者：
Arribas, J. R.
中科院分区：
文献类型：
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作者：
Negredo, A.;de la Calle-Prieto, F.;Arribas, J. R.
克里米亚-刚果出血热（CCHF）是一种广泛分布的病毒性蜱传疾病。在欧洲，仅在欧洲大陆东南部报告了病例。我们报告两个土生土长的情况下，在西班牙。该指示患者通过距卡塞雷斯省300公里的阿维拉省的蜱叮咬获得疾病，2010年在卡塞雷斯省扩增了蜱的病毒RNA。第二名患者是一名护士，她在照顾索引患者时被感染。两人都感染了这种病毒的非洲3系。（由Red de Investigacion Cooperativa en Enfermedades Tropicales [RICET]和欧盟[欧盟]一级对高度危险和新出现病原体的有效反应[EMERGE]资助。
Crimean-Congo hemorrhagic fever (CCHF) is a widely distributed, viral, tickborne disease. In Europe, cases have been reported only in the southeastern part of the continent. We report two autochthonous cases in Spain. The index patient acquired the disease through a tick bite in the province of Avila - 300 km away from the province of Caceres, where viral RNA from ticks was amplified in 2010. The second patient was a nurse who became infected while caring for the index patient. Both were infected with the African 3 lineage of this virus. (Funded by Red de Investigacion Cooperativa en Enfermedades Tropicales [RICET] and Efficient Response to Highly Dangerous and Emerging Pathogens at EU [European Union] Level [EMERGE].)