Is essential tremor predominantly a kinetic or a postural tremor? A clinical and electrophysiological study
Is essential tremor predominantly a kinetic or a postural tremor? A clinical and electrophysiological study
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DOI：
10.1002/mds.10003
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发表时间：
2002-03-01
影响因子：
8.6
通讯作者：
Louis, ED
中科院分区：
文献类型：
--
作者：
Brennan, KC;Jurewicz, EC;Louis, ED
特发性震颤（ET）可能出现姿势性震颤和动作性震颤，但每种震颤的相对作用并不明确。ET在动作性震颤和姿势性震颤方面的定义各不相同。为了研究ET中姿势性震颤和动作性震颤的相对严重程度，对来自诊所的50例ET患者和来自社区的55例患者进行了录像震颤检查。使用经过验证的临床评分量表（评分范围为0 - 3）对动作性震颤和姿势性震颤进行评分。31例患者还接受了加速度测量以精确量化震颤幅度。在诊所病例中，姿势性震颤的平均评分为1.25（标准差为0.89）。动作性震颤的平均评分高出52%（1.90；标准差为0.57；P < 0.001）。社区病例具有相似特征。105例患者中有60%的姿势性震颤评分为0或1（无震颤或低幅度、间歇性震颤）。在诊所病例中，震颤分析期间姿势性震颤的平均幅度为0.51毫米（标准差为0.66毫米），动作性震颤的平均幅度为2.91毫米（标准差为2.11毫米；P < 0.01）。社区病例得到了类似的值。这些定量数据表明，在ET中动作性震颤比姿势性震颤更严重。大多数病例的姿势性震颤轻微或不存在。尽管如此，在许多研究中ET仅被定义为一种姿势性震颤。我们的数据支持在ET的诊断标准中更一致地纳入动作性震颤。（C）2002运动障碍学会
Both postural and kinetic tremors may occur in essential tremor (ET), however the relative contribution of each is not clear. ET has been variably defined with respect to kinetic and postural tremors. To examine the relative severity of postural and kinetic tremors in ET, 50 ET cases from a clinic and 55 from a community underwent a videotaped tremor examination. Kinetic and postural tremors were rated using a validated clinical rating scale (score range, 0-3). Thirty-one cases also underwent accelerometry to precisely quantify tremor amplitude. In clinic cases, the mean postural tremor rating was 1.25 (S.D., 0.89). The mean kinetic tremor rating was 52% higher (1.90; S.D., 0.57; P < 0.001). The community cases had similar characteristics. Sixty percent of the 105 cases had postural tremor ratings scoring 0 or 1 (no tremor or low amplitude, intermittent tremor). In clinic cases, the mean amplitude of postural tremor during tremor analysis was 0.51 mm (S.D., 0.66 mm), and the mean amplitude of kinetic tremor was 2.91 mm (S.D., 2.11 mm; P < 0.01). Similar values were obtained for community cases. These quantitative data suggest that kinetic tremor is more severe than postural tremor in ET. The majority of cases had mild or absent postural tremor. Despite this, ET is defined only as a postural tremor in many studies. Our data argue for a more consistent inclusion of kinetic tremor in diagnostic criteria for ET. (C) 2002 Movement Disorder Society.