Artificial insemination history: hurdles and milestones
Artificial insemination history: hurdles and milestones
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人工授精历史：障碍和里程碑
DOI：
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
J. Robays
中科院分区：
文献类型：
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作者：
W. Ombelet;J. Robays
人工授精与同源（AIH）或供体精液（AID）现在是一种非常流行的治疗程序，用于许多世界各地的不孕妇女。人工授精的基本原理是增加受精点的配子密度。导致今天普遍使用人工授精的一系列事件可以追溯到许多世纪前的科学研究和实验。人类人工授精计划中所使用的现代技术，大多是从奶农对牛的研究中改编而来的。奶农希望用精选的具有优良遗传性状的公牛的精子进行人工授精，从而提高牛奶产量。人类对人工授精重新产生兴趣的主要原因与体外受精早期水洗运动精子制备技术的改进有关。回顾了人工授精的历史，对最重要的障碍和里程碑特别感兴趣。
Artificial insemination with homologous (AIH) or donor semen (AID) is nowadays a very popular treatment procedure used for many subfertile women worldwide. The rationale behind artificial insemination is to increase gamete density at the site of fertilisation. The sequence of events leading to today’s common use of artificial insemination traces back to scientific studies and experimentation many centuries ago. Modern techniques used in human artificial insemination programmes are mostly adapted from the work on cattle by dairy farmers wishing to improve milk production by using artificial insemination with sperm of selected bulls with well chosen genetic traits. The main reason for the renewed interest in artificial insemination in human was associated with the refinement of techniques for the preparation of washed motile spermatozoa in the early years of IVF. The history of artificial insemination is reviewed with particular interest to the most important hurdles and milestones.