MR morphology of triangular fibrocartilage complex: correlation with quantitative MR and biomechanical properties
MR morphology of triangular fibrocartilage complex: correlation with quantitative MR and biomechanical properties
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DOI：
10.1007/s00256-015-2309-z
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发表时间：
2016-04-01
影响因子：
2.1
通讯作者：
Chung, Christine B.
中科院分区：
文献类型：
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作者：
Bae, Won C.;Ruangchaijatuporn, Thumanoon;Chung, Christine B.
为评价三角纤维软骨复合体（TFCC）的病理变化，并与定量MR和生物力学特性进行比较，对5例22-70岁成人腕关节标本进行了3 T磁共振成像，分别采用质子密度加权自旋回波（PD FS）和3D扰相梯度回波（3D SPGR）进行T2和T1 rho定量分析。在8个地理区域，对TFC椎间盘和椎板的形态进行了病理学和定量MR值评价。在形态学PD SE图像上，TFC椎间盘病理学包括退变和撕裂，而椎板病理学包括退变、退变伴叠加撕裂、粘液转化和球形钙化。点状钙化在3D SPGR图像上高度可见，仅见于病理区域。椎间盘病变发生在近端区域比远端区域更频繁。定量MR值在正常样本中最低，并且在病理区域中通常较高。生物力学测试证明了一个相反的关系，与压痕模量高，在正常区域与低MR值。研究的椎板大多是病理性的，需要额外的正常样本来辨别定量变化。这些结果表明，形态学MR，定量MR和生物力学技术来表征TFCC的病理的技术可行性。定量MRI可能是软组织力学特性的合适替代标记，并且是常规形态学MR技术的有用辅助手段。
To evaluate pathology of the triangular fibrocartilage complex (TFCC) using high-resolution morphologic magnetic resonance (MR) imaging, and compare with quantitative MR and biomechanical properties.Five cadaveric wrists (22-70 years) were imaged at 3 T using morphologic (proton density weighted spin echo, PD FS, and 3D spoiled gradient echo, 3D SPGR) and quantitative MR sequences to determine T2 and T1rho properties. In eight geographic regions, morphology of TFC disc and laminae were evaluated for pathology and quantitative MR values. Samples were disarticulated and biomechanical indentation testing was performed on the distal surface of the TFC disc.On morphologic PD SE images, TFC disc pathology included degeneration and tears, while that of the laminae included degeneration, degeneration with superimposed tear, mucinous transformation, and globular calcification. Punctate calcifications were highly visible on 3D SPGR images and found only in pathologic regions. Disc pathology occurred more frequently in proximal regions of the disc than distal regions. Quantitative MR values were lowest in normal samples, and generally higher in pathologic regions. Biomechanical testing demonstrated an inverse relationship, with indentation modulus being high in normal regions with low MR values. The laminae studied were mostly pathologic, and additional normal samples are needed to discern quantitative changes.These results show technical feasibility of morphologic MR, quantitative MR, and biomechanical techniques to characterize pathology of the TFCC. Quantitative MRI may be a suitable surrogate marker of soft tissue mechanical properties, and a useful adjunct to conventional morphologic MR techniques.