FLEXIBLE REGRESSION-MODELS WITH CUBIC-SPLINES
FLEXIBLE REGRESSION-MODELS WITH CUBIC-SPLINES
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DOI:
10.1002/sim.4780080504
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发表时间:
1989-05-01
影响因子:
2
通讯作者:
SIMON, R
中科院分区:
文献类型:
--
作者:
DURRLEMAN, S;SIMON, R
We describe the use of cubic splines in regression models to represent the relationship between the response variable and a vector of covariates. This simple method can help prevent the problems that result from inappropriate linearity assumptions. We compare restricted cubic spline regression to non-parametric procedures for characterizing the relationship between age and survival in the Stanford Heart Transplant data. We also provide an illustrative example in cancer therapeutics.