Macrolide-Resistant Mycoplasma pneumoniae Pneumonia in Adolescents and Adults: Clinical Findings, Drug Susceptibility, and Therapeutic Efficacy

Macrolide-Resistant Mycoplasma pneumoniae Pneumonia in Adolescents and Adults: Clinical Findings, Drug Susceptibility, and Therapeutic Efficacy
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DOI:
10.1128/aac.00737-13
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发表时间:
2013-10-01
影响因子:
4.9
通讯作者:
Okimoto, Niro
Okimoto, Niro
中科院分区:
医学2区
文献类型:
--
作者:
Miyashita, Naoyuki;Akaike, Hiroto;Okimoto, Niro

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我们调查了青少年和成人中 30 名大环内酯类耐药肺炎支原体肺炎患者和 43 名大环内酯类敏感肺炎支原体肺炎患者之间临床表现的差异。两组之间没有观察到临床表现的差异。在耐大环内酯类肺炎支原体肺炎患者中,接受喹诺酮类和米诺环素组的治疗效果比接受大环内酯类药物组更有效(分别为 P = 0.0361 和 P = 0.0237)。
We investigated differences in the clinical findings between 30 patients with macrolide-resistant Mycoplasma pneumoniae pneumonia and 43 patients with macrolide-sensitive M. pneumoniae pneumonia in adolescents and adults. No differences in clinical presentation were observed between the two groups. Among patients with macrolide-resistant Mycoplasma pneumoniae pneumonia, treatment was more effective in the groups that received quinolones and minocycline than in the group that received macrolides (P = 0.0361 and P = 0.0237, respectively).