Mass density images from the diffraction enhanced imaging technique.

Mass density images from the diffraction enhanced imaging technique.
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来自衍射增强成像技术的质量密度图像。

DOI:
10.1118/1.1852794
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发表时间:
2005
期刊:
影响因子:
3.8
通讯作者:
Chapman,D
Chapman,D
中科院分区:
医学3区
文献类型:
--
作者:
Hasnah,MO;Parham,C;Pisano,ED;Zhong,Z;Oltulu,O;Chapman,D

文献摘要

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传统的x射线照相术测量物体的投影x射线衰减。为了获得嵌入特征的对比度,需要使用衰减差异。一般来说,最好的吸收对比度是在X射线能量下获得的,在那里吸收的能量很高,这意味着吸收剂量很高。衍射增强成像(DEI)通过吸收、折射和消光来获得对比度。DEI的折射角图像直观地显示了物体投射电子密度的空间梯度。在软组织成像中,投射电子密度通常与投射质量密度和投射吸收很好地相关,然而,质量密度并不像吸收那样是物体的“能量”依赖属性。这一简单的差异可以导致使用较少的X射线曝光或剂量进行成像。此外,质量密度图像可以直接与传统的射线照相进行比较(即信噪比较)。给出了质量密度图像的获取方法、实验结果,并将该方法应用于乳腺癌的成像。
Conventional x‐ray radiography measures the projected x‐ray attenuation of an object. It requires attenuation differences to obtain contrast of embedded features. In general, the best absorption contrast is obtained at x‐ray energies where the absorption is high, meaning a high absorbed dose. Diffraction‐enhanced imaging (DEI) derives contrast from absorption, refraction, and extinction. The refraction angle image of DEI visualizes the spatial gradient of the projected electron density of the object. The projected electron density often correlates well with the projected mass density and projected absorption in soft‐tissue imaging, yet the mass density is not an “energy”‐dependent property of the object, as is the case of absorption. This simple difference can lead to imaging with less x‐ray exposure or dose. In addition, the mass density image can be directly compared (i.e., a signal‐to‐noise comparison) with conventional radiography. We present the method of obtaining the mass density image, the results of experiments in which comparisons are made with radiography, and an application of the method to breast cancer imaging.