Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women
Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women
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DOI：
10.1359/jbmr.061003
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发表时间：
2007-01-01
影响因子：
6.2
通讯作者：
Akesson, Kristina
中科院分区：
文献类型：
--
作者：
Gerdhem, Paul;Ivaska, Kaisa K.;Akesson, Kristina
同型半胱氨酸被认为是骨折的危险因素，但因果关系尚不清楚。在OPRA研究的996名女性中，高同型半胱氨酸水平与基线时高骨标志物水平和低BMD相关。在平均7年的随访中，高同型半胱氨酸水平与死亡率相关，但与骨折风险无明显相关性。
Homocysteine has been suggested to be a risk factor for fracture, but the causal relationship is not clear. In 996 women from the OPRA study, high homocysteine level was associated with high bone marker levels and low BMD at baseline. During a mean 7-year follow-up, high homocysteine level was associated with mortality, but no clear association to fracture risk existed.