General models of multilocus evolution.
General models of multilocus evolution.
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多位点进化的一般模型。
作者：
M. Kirkpatrick;T. Johnson;N. Barton
1991年，巴顿和图雷利发展了递归来描述多位点系统在任意选择形式下的进化。本文概括了他们的方法，允许任意模式的遗传，包括二倍体，多倍体，性连锁，细胞质遗传，基因组印记。该框架还扩展到允许其他确定性的进化力量，包括迁移和突变。精确的递归，充分描述了人口的状态，这些都是在计算机代数包（可在网上http：//helios.bto.ed.ac.uk/evolgen）。尽管我们的框架具有一般性，但它可以通过两个方程精确地描述进化动力学。这些递归可以进一步简化使用“准链接平衡”（QLE）近似。我们说明的方法，发现自然选择，性选择，突变和迁移的遗传组成的人口的影响。
In 1991, Barton and Turelli developed recursions to describe the evolution of multilocus systems under arbitrary forms of selection. This article generalizes their approach to allow for arbitrary modes of inheritance, including diploidy, polyploidy, sex linkage, cytoplasmic inheritance, and genomic imprinting. The framework is also extended to allow for other deterministic evolutionary forces, including migration and mutation. Exact recursions that fully describe the state of the population are presented; these are implemented in a computer algebra package (available on the Web at http://helios.bto.ed.ac.uk/evolgen). Despite the generality of our framework, it can describe evolutionary dynamics exactly by just two equations. These recursions can be further simplified using a "quasi-linkage equilibrium" (QLE) approximation. We illustrate the methods by finding the effect of natural selection, sexual selection, mutation, and migration on the genetic composition of a population.