Relationships among bone mineral densities, static alignment and dynamic load in patients with medial compartment knee osteoarthritis
Relationships among bone mineral densities, static alignment and dynamic load in patients with medial compartment knee osteoarthritis
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DOI：
10.1093/rheumatology/40.5.499
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发表时间：
2001-05-01
期刊：
影响因子：
5.5
通讯作者：
Nose, Y
中科院分区：
文献类型：
--
作者：
Wada, M;Maezawa, Y;Nose, Y
目标。目的探讨胫股骨性关节炎(OA)患者骨密度(BMD)、静态对位与膝关节内收力矩之间的关系。对69例膝关节内侧骨性关节炎患者进行了X线片评估、步态分析和胫骨近端及腰椎骨密度测量。胫骨近端内、外侧部的骨矿分布与最大内收力矩和机械轴呈显著正相关。此外，内收力矩与机械轴显著相关。但腰椎骨密度和胫骨近端后前部骨矿分布与其他测量指标均无相关性。我们的结果表明，胫骨近端的骨矿分布直接受到影响，而腰椎骨密度不受膝关节周围的局部机械应力的影响。
Objective. To investigate the relationships among bone mineral density (BMD), static alignment and the adduction moment of the knee in patients with tibiofemoral osteoarthritis (OA).Methods. Sixty-nine patients with medial compartment knee OA underwent radiographic evaluation, gait analysis and BMD measurements at the proximal tibia and lumbar spine.Results. The bone mineral distribution of the medial to lateral part of the proximal tibia correlated significantly with the peak knee adduction moment and the mechanical axis. Furthermore, the adduction moment correlated significantly with the mechanical axis. However, the BMD of the lumbar spine and the bone mineral distribution of the posterior to anterior part of the proximal tibia did not correlate with any other measurement.Conclusions. Our results suggest that the bone mineral distribution of the proximal tibia is directly affected but lumbar BMD is not influenced by the local mechanical stress around the knee with medial compartment OA.