KPC-Like Carbapenemase-Producing Enterobacteriaceae Colonizing Patients in Europe and Israel
KPC-Like Carbapenemase-Producing Enterobacteriaceae Colonizing Patients in Europe and Israel
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DOI：
10.1128/aac.02756-15
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发表时间：
2016-03-01
影响因子：
4.9
通讯作者：
Gniadkowski, M.
中科院分区：
文献类型：
--
作者：
Baraniak, A.;Izdebski, R.;Gniadkowski, M.
在2008-2011年的一项调查中，对欧洲和以色列18个医院单位的17,945名患者进行了肺炎克雷伯菌碳青霉烯酶（KPC）产生肠杆菌科的携带筛查，结果鉴定出124名阳性患者。分离株以肺炎克雷伯菌序列258型（ST258） KPC-2型和ST512 KPC-3型为主，分别主要来自希腊和意大利，而以色列分离株具有不同的种、克隆和KPC变体。观察到多种bla（KPC）平台，其中以Tn4401a转座子中含有bla（KPC 2/ 3）基因的IncFII(K)-FIBK质粒为主。
In a 2008-2011 survey, 17,945 patients in 18 hospital units in Europe and Israel were screened for carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae, resulting in identification of 124 positive patients. The isolates were dominated by Klebsiella pneumoniae sequence type 258 (ST258) KPC-2 and ST512 KPC-3, mainly from Greece and Italy, respectively, whereas Israeli isolates were of diverse species, clones, and KPC variants. Various bla(KPC) platforms were observed, among which IncFII(K)-FIBK plasmids with bla(KPC 2/ 3) genes in the Tn4401a transposon prevailed.