Association Between Obesity, Flow Rate of Whole Saliva, and Dental Caries in Adolescents
Association Between Obesity, Flow Rate of Whole Saliva, and Dental Caries in Adolescents
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DOI：
10.1038/oby.2010.63
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发表时间：
2010-12-01
期刊：
影响因子：
6.9
通讯作者：
Marcus, Claude
中科院分区：
文献类型：
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作者：
Modeer, Thomas;Blomberg, Cecilia C.;Marcus, Claude
在一项横断面研究设计中，我们检验了儿童肥胖是否与受刺激的全唾液流量减少和龋齿有关的假设。研究人员对平均年龄14.5岁的肥胖青少年（n = 65）和平均年龄14.2岁的正常体重青少年（n = 65）进行了龋齿、可见菌斑堆积（可见菌斑指数（VPI%））、牙探出血引起的牙龈炎症（BOP%）等方面的临床检查，并回答了一份关于病史、用药、口腔卫生习惯、吸烟习惯和社会人口背景的问卷。测定受刺激全唾液流速（ml/min）。计算BMI并根据年龄和性别进行调整（BMI-sds）。肥胖组腐烂面数（DS）为0.7比0.1 (P = 0.008)，刺激全唾液流速（1.2比2.0 ml/min）较低（P < 0.001）。肥胖患者中，17例VPI% >25, 21例BOP% >25，而体重正常的患者只有5例（P值分别为0.005和0）（P = 0.002； OR为1.31），这些关联未被任何研究变量所混淆。结果表明，儿童肥胖与受刺激的全唾液流速降低和龋齿有关，进一步强化了肥胖对儿童口腔健康的负面影响。
In a cross-sectional study design, we test the hypothesis whether childhood obesity is associated with reduced flow rate of stimulated whole saliva and dental caries. Obese adolescents (n = 65) with a mean age of 14.5 years and normal weight subjects (n = 65) with a mean age of 14.2 years were clinically examined with respect to dental caries, visible plaque accumulation (visible plaque index (VPI%)), gingival inflammation in terms of bleeding on probing (BOP%) as well as answered a questionnaire concerning medical history, medication, oral hygiene habits, smoking habits, and sociodemographic background. The flow rate of stimulated whole saliva (ml/min) was determined. BMI was calculated and adjusted for age and gender (BMI-sds). The obese subjects exhibited higher number of decayed surfaces (DS), 0.7 vs. 0.1 (P = 0.008) and lower flow rate of stimulated whole saliva 1.2 vs. 2.0 ml/min (P < 0.001). Of obese patients, 17 subjects had VPI% >25 and 21 had BOP% >25, both compared to only 5 subjects of the normal weight with P values of 0.005 and 0) (P = 0.002; OR 1.31) and the associations were not found to be confounded by any of the studied variables. The results indicate that childhood obesity is associated with reduced flow rate of stimulated whole saliva and dental caries and further strengthens obesity's negative effect on children's oral health.