Validation of stroke diagnosis in the National Hospital Discharge Register and the Register of Causes of Death in Finland
Validation of stroke diagnosis in the National Hospital Discharge Register and the Register of Causes of Death in Finland
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DOI：
10.1023/a:1007504310431
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发表时间：
1999-02-01
影响因子：
13.6
通讯作者：
Heinonen, OP
中科院分区：
文献类型：
--
作者：
Leppälä, JM;Virtamo, J;Heinonen, OP
在芬兰的546名中年男性中，对国家医院出院登记处和死亡原因登记处中中风诊断的有效性进行了检查。受试者是α-生育酚、β-胡萝卜素癌症预防研究的脑血管疾病病例，并通过与登记册的记录链接进行识别。总之，使用从全国卒中调查和WHO MONICA研究的分类中修改的特定标准，审查了375起以脑血管疾病作为出院诊断的事件和218起以脑血管疾病作为潜在死亡原因的事件。对于医院卒中诊断，90%的患者对所有卒中的诊断一致，79%的患者对蛛网膜下腔出血的诊断一致，82%的患者对脑出血的诊断一致，90%的患者对脑梗死的诊断一致。卒中作为潜在死亡原因的一致率分别为97%、95%、91%和92%。分别有1%和3%的卒中事件的数据不足以进行审查。年龄、观察年份和试验补充α-生育酚或β-胡萝卜素对有效性没有影响。总之，在医院诊断和死亡原因登记中，卒中诊断的有效性良好，证明其用于流行病学研究的终点评估是合理的。
The validity of stroke diagnosis in the National Hospital Discharge Register and the Register of Causes of Death was examined among 546 middle-aged men in Finland. The subjects were cases of cerebrovascular diseases of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study and identified by record linkage to the registers. In all, 375 events with cerebrovascular disease as hospital discharge diagnosis and 218 events with cerebrovascular disease as the underlying cause of death were reviewed using specific criteria modified from the classifications of the National Survey of Stroke and the WHO MONICA Study. For hospital stroke diagnoses, there was agreement on diagnosis for all strokes in 90%, for subarachnoid hemorrhage in 79%, intracerebral hemorrhage in 82%, and cerebral infarction in 90%. The respective agreement rates for stroke as the underlying cause of death were 97%, 95%, 91%, and 92%. The data were insufficient for review in 1% and 3% of the stroke events, respectively. Age, observation year and trial supplementation with alpha -tocopherol or beta-carotene had no effect on validity. In conclusion, the validity of stroke diagnosis was good in registers of hospital diagnoses and causes of death justifying their use for endpoint assessment in epidemiological studies.