OOCYTE DONATION IN 61 PATIENTS
OOCYTE DONATION IN 61 PATIENTS
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DOI：
10.1016/s0140-6736(89)92762-1
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发表时间：
1989-05
期刊：
影响因子：
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通讯作者：
P. Serhal;I. Craft
中科院分区：
文献类型：
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作者：
P. Serhal;I. Craft
通过输卵管内配子移植对 61 名女性进行卵母细胞捐赠，其中 34 名女性患有闭经。捐献者的平均年龄为 32 岁（范围 23-38 岁）。 75 个治疗周期实现了 29 例临床妊娠，其中 21 例足月，3 例继续妊娠，5 例流产（3 例流产，1 例输卵管流产，1 例宫颈流产）。 11 名（38%）怀孕女性年龄超过 42 岁。当移植四个以上的卵母细胞时，许多妊娠都是多胞胎。 8 例（38%）足月妊娠并发先兆子痫毒血症。当从年轻女性身上获得卵母细胞时，无论受卵者的年龄如何，生育潜力都很高。
Oocyte donation was performed by gamete intrafallopian transfer in 61 women, 34 of whom were amenorrhoeic. The mean age of the donors was 32 years (range 23-38). Seventy-five treatment cycles gave 29 clinical pregnancies, of which 21 reached term, 3 continue, and 5 were lost (3 miscarriages, 1 tubal, and 1 cervical). 11 (38%) of the women who became pregnant were over 42 years old. When more than four oocytes were transferred, many of the pregnancies were multiple. 8(38%) of the pregnancies that came to term were complicated by pre-eclamptic toxaemia. When oocytes are obtained from young women, the fertility potential is high irrespective of the recipient's age.