Aneurysm permeability following coil embolization: packing density and coil distribution
Aneurysm permeability following coil embolization: packing density and coil distribution
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DOI：
10.1136/neurintsurg-2014-011289
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发表时间：
2015-09-01
影响因子：
4.8
通讯作者：
Gounis, Matthew J.
中科院分区：
文献类型：
--
作者：
Chueh, Ju-Yu;Vedantham, Srinivasan;Gounis, Matthew J.
背景：线圈栓塞后持久动脉瘤闭塞的发生率差异很大，需要对线圈质量力学有更好的了解。本研究的目的是评估填充密度和线圈均匀性对动脉瘤通透性的影响。方法采用Guglielmi可拆卸线圈或Target线圈对动脉瘤模型进行卷绕。渗透率是通过测量通过线圈质量的微球与工作流体中微球的比值来评估的。对含有线圈肿块的动脉瘤进行切片，进行图像分析，以确定其表面积分数和线圈均匀性。结果所有动脉瘤均成卷，充填密度不低于27%。填料密度，圆顶和颈部的表面积分数和圆顶的均匀性显著相关(p
Background Rates of durable aneurysm occlusion following coil embolization vary widely, and a better understanding of coil mass mechanics is desired. The goal of this study is to evaluate the impact of packing density and coil uniformity on aneurysm permeability.Methods Aneurysm models were coiled using either Guglielmi detachable coils or Target coils. The permeability was assessed by taking the ratio of microspheres passing through the coil mass to those in the working fluid. Aneurysms containing coil masses were sectioned for image analysis to determine surface area fraction and coil uniformity.Results All aneurysms were coiled to a packing density of at least 27%. Packing density, surface area fraction of the dome and neck, and uniformity of the dome were significantly correlated (p