Association study of polymorphisms in SOCS family genes with type 1 diabetes mellitus
Association study of polymorphisms in SOCS family genes with type 1 diabetes mellitus
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DOI：
10.1111/j.1744-313x.2006.00563.x
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发表时间：
2006-02-01
影响因子：
2.2
通讯作者：
Hara, T
中科院分区：
文献类型：
--
作者：
Ni, R;Ihara, K;Hara, T
细胞因子信号转导抑制因子(SoCs)蛋白在细胞因子信号负调控中发挥重要作用。我们首先寻找SOCS-1、SOCS-3和SOCS-5基因的多态，并研究这些多态与1型糖尿病(T1D)的关系。因此，我们没有发现SOCS基因和T1D之间有任何显著的关联。
Suppressors of cytokine signalling (SOCS) proteins play important roles in the negative regulation of cytokine signal. We first searched for polymorphisms in SOCS-1, SOCS-3 and SOCS-5 genes, and examined the association of the polymorphisms with type 1 diabetes (T1D). As a result, we did not find any significant associations between SOCS genes and T1D.