Sensitive, specific polymorphism discovery in bacteria using massively parallel sequencing.
Sensitive, specific polymorphism discovery in bacteria using massively parallel sequencing.
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使用大量平行测序在细菌中发现敏感的特异性多态性。
DOI：
10.1038/nmeth.1286
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发表时间：
2009-01
期刊：
影响因子：
48
通讯作者：
Jaffe, David B.
中科院分区：
文献类型：
--
作者：
Nusbaum, Chad;Ohsumi, Toshiro K.;Gomez, James;Aquadro, John;Victor, Thomas C.;Warren, Robert M.;Hung, Deborah T.;Birren, Bruce W.;Lander, Eric S.;Jaffe, David B.
Our variant ascertainment algorithm VAAL uses massively parallel DNA sequence data to identify differences between bacterial genomes at high sensitivity and specificity. VAAL found ~98% of differences (including large indels) between pairs of strains from three species while calling no false positives. Further, VAAL pinpointed a single mutation between Vibrio genomes, identifying an antibiotic’s site of action by finding the difference(s) between a drug sensitive strain and a resistant derivative.
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影响因子：
30.8
作者：
Holt, Kathryn E.;Parkhill, Julian;Mazzoni, Camila J.;Roumagnac, Philippe;Weill, Francois-Xavier;Goodhead, Ian;Rance, Richard;Baker, Stephen;Maskell, Duncan J.;Wain, John;Dolecek, Christiane;Achtman, Mark;Dougan, Gordon
通讯作者：
Dougan, Gordon
影响因子：
56.9
作者：
Shendure, J;Porreca, GJ;Church, GM
通讯作者：
Church, GM
DOI：
10.1073/pnas.0510740103
发表时间：
2006-05-23
影响因子：
11.1
作者：
Velicer, Gregory J.;Raddatz, Guenter;Schuster, Stephan C.
通讯作者：
Schuster, Stephan C.
影响因子：
7
作者：
Li, Heng;Ruan, Jue;Durbin, Richard
通讯作者：
Durbin, Richard
影响因子：
56.9
作者：
Andries, K;Verhasselt, P;Jarlier, V
通讯作者：
Jarlier, V