Effect of Repeated X-irradiation on the Process of Degradation of Deoxyribonucleic Acid

Effect of Repeated X-irradiation on the Process of Degradation of Deoxyribonucleic Acid
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反复X射线照射对脱氧核糖核酸降解过程的影响

DOI:
10.1038/202106a0
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发表时间:
1964
期刊:
影响因子:
64.8
通讯作者:
D. Novak
D. Novak
中科院分区:
综合性期刊1区
文献类型:
--
作者:
B. Miletić;Ž. Kućan;D. Novak

文献摘要

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X 射线照射会导致暴露于中剂量和高剂量辐射的细菌中 DNA 降解1,2。低剂量对 DNA 的合成没有明显影响,降解过程仅在 3-4 kr 后开始。然而,我们观察到,自 24 kr 和 32 kr 剂量起,效果存在饱和。与较低剂量引起几乎相同程度的 DNA 降解。 Stuy3 发现受辐射的细菌也有同样的效果,但这些细菌在辐射后就会挨饿。
X-IRRADIATION causes the degradation of DNA in bacteria exposed to medium and high doses of radiation1,2. Low doses have no visible effect on the synthesis of DNA, the degradative process starting only after 3–4 kr. However, we observed that there exists a saturation in the effect since doses of 24 and 32 kr. cause almost the same degree of degradation of DNA as do the lower doses. Stuy3 has found the same effect with irradiated bacteria which were, however, starved after irradiation.