Slow transit constipation: a review of a colonic functional disorder.
Slow transit constipation: a review of a colonic functional disorder.
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DOI：
10.1055/s-2008-1075864
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发表时间：
2008-05-01
影响因子：
1.4
通讯作者：
Nogueras, Juan J
中科院分区：
文献类型：
--
作者：
Frattini, Jared C;Nogueras, Juan J
便秘是一种常见的胃肠道疾病，可导致严重的身体和心理问题。它被分为慢传输型便秘、正常传输型便秘和排便障碍。便秘的定义和病理生理学都不清楚，但试图描述这三种类型中的每一种。慢传输型便秘是一种功能性结肠疾病，约占便秘患者的15 - 30%。理论上的病因是自主神经和肠神经系统紊乱和/或神经内分泌系统功能障碍。慢传输型便秘可以通过完整的病史、体格检查和一系列特定的诊断研究来诊断。一旦诊断得到肯定，医疗管理失败，有几种治疗方案。生物反馈、骶神经刺激、节段性结肠切除术和结肠次全切除术以及各种结肠病变都已被使用。在这些治疗方案中，结肠次全切除术和回肠直肠吻合术是最有效的，有数据支持其使用。
Constipation is a common gastrointestinal complaint that can cause significant physical and psychosocial problems. It has been categorized as slow transit constipation, normal transit constipation, and obstructed defecation. Both the definition and pathophysiology of constipation are unclear, but attempts to describe each of the three types have been made. Slow transit constipation, a functional colonic disorder represents approximately 15 to 30% of constipated patients. The theorized etiologies are disorders of the autonomic and enteric nervous system and/or a dysfunctional neuroendocrine system. Slow transit constipation can be diagnosed with a complete history, physical exam, and a battery of specific diagnostic studies. Once the diagnosis is affirmed and medical management has failed, there are several treatment options. Biofeedback, sacral nerve stimulation, segmental colectomy, and subtotal colectomy with various anastomoses have all been used. Of those treatment options, a subtotal colectomy with ileorectal anastomosis is the most efficacious with the data to support its use.