Uterine fibroid pseudocapsule studied by transmission electron microscopy
Uterine fibroid pseudocapsule studied by transmission electron microscopy
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DOI：
10.1016/j.ejogrb.2012.02.017
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发表时间：
2012-06-01
影响因子：
2.6
通讯作者：
Tinelli, Andrea
中科院分区：
文献类型：
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作者：
Malvasi, Antonio;Cavallotti, Carlo;Tinelli, Andrea
目的：肌瘤假包膜是一种包围子宫肌瘤的结构，将其与子宫组织分开，并包含富含神经递质的血管网络，如神经血管束。作者研究了组成的纤维瘤pseudocapsule using electron microscopic.Study design：20名非妊娠患者提交腹腔镜子宫肌瘤切除术的囊内方法和样品的去除pseudocapsules进行了分析，使用透射电镜microscopic.Results：在超微结构水平的pseudocapsule细胞具有平滑肌细胞的功能，类似于子宫肌层。结论：子宫肌瘤的超微结构特征提示在切除肌瘤时应保留肌瘤的假包膜。这项研究证实了初步的证据表明，伪胶囊含有神经肽及其相关的纤维，作为一个神经血管束。在肌瘤切除过程中，外科医生的行为应该是小心地控制和保留这些肌肉周围组织，以尽可能地保留子宫肌层。(C)2012爱思唯尔爱尔兰有限公司保留所有权利。
Objective: The fibroid pseudocapsule is a structure which surrounds the uterine fibroid, separates it from the uterine tissue and contains a vascular network rich in neurotransmitters like a neurovascular bundle. The authors examined the composition of the fibroid pseudocapsule using electron microscopy.Study design: Twenty non-pregnant patients were submitted to laparoscopic myomectomy by the intracapsular method and samples of the removed pseudocapsules were analyzed using transmission electron microscopy.Results: At the ultrastructural level the pseudocapsule cells have the features of smooth muscle cells similar to the myometrium. So, the pseudocapsules are part of the myometrium which compresses the leiomyoma.Conclusion: This ultrastructural feature suggests that when removing fibroids their pseudocapsules should be preserved. This study confirms preliminary evidence that pseudocapsules contain neuropeptides together with their related fibers, as a neurovascular bundle. The surgeon's behavior should be directed to carefully control and spare this muscular surrounding tissue during fibroid excision, in order to preserve the myometrium as much as possible. (C) 2012 Elsevier Ireland Ltd. All rights reserved.