Gastric cancer mortality rates among US and foreign-born persons: United States 2005-2014
Gastric cancer mortality rates among US and foreign-born persons: United States 2005-2014
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DOI：
10.1007/s10120-019-00944-w
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发表时间：
2019-09-01
期刊：
影响因子：
7.4
通讯作者：
Saraiya, Mona
中科院分区：
文献类型：
--
作者：
Hallowell, Benjamin D.;Endeshaw, Meheret;Saraiya, Mona
背景从历史上看，与美国出生的人相比，在美国出生的外国人死于胃癌的风险较高。这主要是由于他们移民到美国之前发生的因素，包括饮食和潜在的H。幽门感染方法2005年至2014年的全国死亡率数据来自CDC的国家卫生统计中心。年度人口估计数来自美国人口普查局对外国出生和美国出生的人进行的美国社区调查。按出生地、年龄、人种/种族和地理位置分层计算经年龄校正的胃癌死亡率和率比（RR）。从2005年到2014年，美国发生了111，718例恶性胃癌死亡，其中24，583例（22%）发生在外国出生的个体中。总体而言，与美国出生的个体相比，外国出生的个体的死亡率更高（RR 1.82; 95% CI 1.80，1.85），并且在按性别、年龄和地理位置分层后，这种差异仍然存在。然而，这一发现主要是由于美国出生的白人胃癌死亡率较低，在所有其他外国出生和美国出生的群体中观察到类似的死亡率。研究期间，胃癌死亡率总体显著下降（AAPC - 2.50; 95% CI - 3.21，- 1.79），在美国出生（AAPC - 2.81; 95% CI - 3.55，- 2.07）和外国出生（AAPC - 2.53; 95% CI - 3.20，- 1.86）人群中观察到显著下降。结论：努力降低胃癌危险因素的患病率，有助于减少在外国出生的个人和美国出生的少数民族群体中观察到的负担增加。
Background Historically, foreign-born individuals in the US have had an elevated risk of dying from gastric cancer when compared to US-born individuals. This is primarily due to factors that occur prior to their immigration to the US, including diet and underlying risk of H. pylori infection. Methods National mortality data from 2005 to 2014 were obtained from the CDC's National Center for Health Statistics. Annual population estimates were obtained from the US Census Bureau's American Community Survey for foreign-born and US-born persons. Age-adjusted gastric cancer mortality rates and rate ratios (RR) were calculated stratified by birth place, age, race/ethnicity, and geographic location. Results From 2005 to 2014, 111,718 deaths from malignant gastric cancer occurred in the US, of which 24,583 (22%) occurred among foreign-born individuals. Overall, foreign-born individuals had higher mortality rates compared with US-born individuals (RR 1.82; 95% CI 1.80, 1.85) and this difference remained after stratifying by sex, age, and geographic location. However, this finding was primarily driven by the low rate of gastric cancer mortality among US-born whites, with similar mortality rates observed among all other foreign-born and US-born groups. Gastric cancer mortality rates significantly decreased during the study period overall (AAPC - 2.50; 95% CI - 3.21, - 1.79) with significant declines observed among US-born (AAPC - 2.81; 95% CI - 3.55, - 2.07) and the foreign-born (AAPC - 2.53; 95% CI - 3.20, - 1.86) population. Conclusions Efforts directed at reducing the prevalence of gastric cancer risk factors could help reduce the elevated burden observed among foreign-born individuals and US-born minority groups.