Rate of actual metal allergy prior to dental treatment in subjects complaining of possible metal allergy
Rate of actual metal allergy prior to dental treatment in subjects complaining of possible metal allergy
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DOI：
10.12932/ap-241018-0425
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发表时间：
2020-09-01
影响因子：
5
通讯作者：
Furue, Masutaka
中科院分区：
文献类型：
--
作者：
Itoh, Eriko;Furumura, Minao;Furue, Masutaka
背景资料：对于自报金属过敏或担心可能有这种过敏的患者，牙科治疗通常很困难;这类患者经常接受皮肤科咨询进行金属斑贴试验（PT）。目的：本研究比较了金属过敏原的PT结果及其在福冈牙科大学医院就诊患者中的临床相关性。方法：我们进行PT与金属过敏原的患者口腔粘膜或皮肤相关的症状，或那些关心的不良事件与即将到来的牙科treatment.Results：59例患者进行金属过敏原斑贴试验。34例（58.8%）患者自报金属过敏。关于合并症，特应性皮炎是最常见的（7例），其次是手部湿疹、掌跖脓疱病、扁平苔藓和口腔感觉异常。总体而言，59例病例中有25例至少有1个阳性PT反应。最常见的阳性过敏原是硫酸镍（17例），其次是氯化钴、氯化锌和氯化钯。自报金属过敏者的金属PT阳性率明显高于自报金属过敏者（P < 0.001）。其他合并症与那些有或没有自我报告的金属过敏无显著相关性。结论：自报金属过敏的患者表现出更多的金属PT反应比那些没有这个。五分之一的人没有这表现出积极的金属PT反应，这意味着PT的重要性，无论是有和没有自我报告的金属过敏。PT结果有助于为未来的修复和正畸治疗选择牙科金属。
Background: Dental treatment for patients with self-reported metal allergy or concern about the possibility of having such an allergy is often difficult; such patients often undergo dermatological consultations for metal patch test (PT).Objective: This study compared PT results for metal allergens and the clinical relevance of this among patients visiting Fukuoka Dental College Hospital.Methods: We performed PT with metal allergens on patients with oral mucosa- or skin-related symptoms, or those concerned about adverse events associated with upcoming dental treatment.Results: Fifty-nine patients were patch-tested with metal allergens. Thirty-four cases (58.8%) had self-reported metal allergy. Regarding comorbidities, atopic dermatitis was the most common (7 cases), followed by hand eczema, palmoplantar pustulosis, lichen planus, and abnormal sensation in the mouth. Overall, 25 of 59 cases had at least one positive PT reaction. The most common positive allergen was nickel sulfate (17 cases), followed by cobalt chloride, zinc chloride, and palladium chloride. The rate of positivity of metal PT was significantly higher in the self-reported metal allergy cases than in the others (P < 0.001). Other comorbidities were not significantly associated with those with or without self-reported metal allergy. Five of those without self-reported metal allergy showed positive PT reaction.Conclusion: Patients with self-reported metal allergy exhibited more metal PT reactions than those without this. One fifth of those without this showed positive metal PT reaction, implying the importance of PT for both with and without self-reported metal allergy. PT results are helpful for selecting dental metals for future prosthetic and orthodontic treatments.