CsrA modulates luxR transcript levels in Vibrio fischeri.
CsrA modulates luxR transcript levels in Vibrio fischeri.
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DOI:
10.1111/j.1574-6968.2012.02499.x
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发表时间:
2012-04
影响因子:
2.1
通讯作者:
Stevens AM
中科院分区:
文献类型:
--
作者:
Williams JW;Ritter AL;Stevens AM
The quorum-sensing and CsrA regulons of Vibrios control overlapping cellular functions during growth. Hence, the potential exists for regulatory network interactions between the pathways that enable them to be coordinately controlled. In Vibrio cholerae, CsrA indirectly modulates the activity of LuxO in the quorum-sensing signaling pathway. In this study, it was demonstrated that in Vibrio fischeri, CsrA causes an increase in the transcript levels of a downstream quorum-sensing regulatory gene, luxR, which does not exist in the V. cholerae system. In V. fischeri, the increase in luxR transcripts caused by CsrA does not depend on the LitR transcriptional activator nor does the CsrA effect seem to occur through the global regulator cAMP-CRP. Thus there appears to be more than one mechanism whereby the CsrA and quorum-sensing pathways integrate regulatory outputs in Vibrios.
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影响因子:
3.2
作者:
Studer, Sarah V.;Mandel, Mark J.;Ruby, Edward G.
通讯作者:
Ruby, Edward G.
影响因子:
3.2
作者:
DUNLAP, PV;GREENBERG, EP
通讯作者:
GREENBERG, EP
DOI:
10.1073/pnas.81.13.4154
发表时间:
1984-01-01
期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子:
--
作者:
ENGEBRECHT, J;SILVERMAN, M
通讯作者:
SILVERMAN, M
影响因子:
2.8
作者:
Bose, Jeffrey L.;Rosenberg, Charles S.;Stabb, Eric V.
通讯作者:
Stabb, Eric V.
影响因子:
3.6
作者:
Bose, Jeffrey L.;Kim, Unmi;Stabb, Eric V.
通讯作者:
Stabb, Eric V.