A syringic acid derivative and two iridoid glycosides from the roots of Stachys geobombycis and their antioxidant properties

A syringic acid derivative and two iridoid glycosides from the roots of Stachys geobombycis and their antioxidant properties
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DOI:
10.1080/14786419.2017.1405413
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发表时间:
2019-03
影响因子:
2.2
通讯作者:
Xian-Li Zhou;Sixin Huang;Peng-Cheng Wang;Qin Luo;Xiao Huang;Qing Xu;Jiangke Qin;Cheng-Qin Liang;Xu Chen
Xian-Li Zhou;Sixin Huang;Peng-Cheng Wang;Qin Luo;Xiao Huang;Qing Xu;Jiangke Qin;Cheng-Qin Liang;Xu Chen
中科院分区:
化学3区
文献类型:
--
作者:
Xian-Li Zhou;Sixin Huang;Peng-Cheng Wang;Qin Luo;Xiao Huang;Qing Xu;Jiangke Qin;Cheng-Qin Liang;Xu Chen

文献摘要

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摘要从地蚕(Stachys geobombycis)根中分离得到一个新的金合欢酸衍生物stageobester A(1)和两个环烯醚萜苷类化合物,其中包括一个新的环烯醚萜苷stageoboside A(2)。它们的结构被阐明的基础上,光谱方法,包括广泛的NMR和MS光谱。此外,所有的分离物进行了测试,其抗氧化能力。化合物1和2对DPPH自由基具有一定的抗氧化活性,IC 50分别为113.33 ± 1.53和40.33 ± 2.08 mg/L。
Abstract A new derivative of syringic acid, stageobester A (1) and two iridoid glycosides which including a new one, stageoboside A (2), were isolated from the roots of Stachys geobombycis. Their structures were elucidated on the basis of spectroscopic methods, including extensive NMR and MS spectra. In addition, all the isolates were tested for their antioxidant capacity. Compounds 1 and 2 showed moderate antioxidant activities against DPPH radical, with IC50 values of 113.33 ± 1.53 and 40.33 ± 2.08 mg/L, respectively.